Pathogenic mechanisms and therapeutic potential

Project Objectives

The project focuses on the role of the endocannabinoid degrading enzyme FAAH (fatty acid amide hydrolase) as a potential molecular target in Alzheimer’s disease, in order to: i) better understand the pathogenic mechanisms of this condition; ii) identify early symptoms of the disease; and iii) develop new therapeutic strategies.

Start/End date

2018 - 2020

Principal Investigator

Prof. Mauro Maccarrone - Coordinator

Host Institution

Campus Bio-Medico University of Rome

Other Institutions involved

  • Consiglio Nazionale delle Ricerche
  • Sapienza Università di Roma
  • Università degli Studi di Roma "Tor Vergata"
  • Università degli Studi di Teramo

Source of funding

Ministero dell’Istruzione, dell’Università e della ricerca (MIUR)