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Projects
Planned projects only
In progress
Impact of the InMed compounds on the endocannabinoid system of human keratinocytes and on their biological functions
01 / 01 / 2019
Project Objectives The project aims at investigating the potential role of different InMed Pharmaceuticals proprietary compounds on the modulation of the various elements of the endocannabinoid syste...
In progress
The endocannabinoid system in Alzheimer’s disease
01 / 01 / 2018
Pathogenic mechanisms and therapeutic potential Project Objectives The project focuses on the role of the endocannabinoid degrading enzyme FAAH (fatty acid amide hydrolase) as a potential molecular ...
In progress
In vitro characterization of MAGL inhibitors
01 / 01 / 2018
Project Objectives The project aims at exploring the ability of new chemical entities to inhibit monoacylglycerol lipase (MAGL), a key enzyme that regulates the production of inflammatory mediators t...
In progress
Specialized pro-resolving lipid mediators as a new therapeutic strategy in the resolution of the adaptive immune response in multiple sclerosis
01 / 01 / 2018
Project Objectives The projects aims at studying the ability of crucial specialized pro-resolving lipid mediators, such as resolving D1, resolving D2 and maresin 1, to restore the altered balance bet...
Concluded
Oxidized lipidome
10 / 11 / 2014
Oxidized lipidome: the unspoken language of non-apoptotic cell death Project Objectives To decipher the molecular mechanisms of necrotic-apoptotic cell death, with particular refe...
Concluded
Impact of phyto-cannabinoids
10 / 11 / 2014
Impact of phyto-cannabinoids on the epigenetic regulation of diabetes Project Objectives To define the epigenetic effects of natural compounds (phytocannabinoids), which are commonly us...
Concluded
Cells-on-chip technologies
10 / 11 / 2014
Cells-on-chip technologies for the study of the endocannabinoid system in an in vitro model of tumor/immune system interaction Project Objectives The project aims at developing advanced...
Concluded
Cutaneous endocannabinoid system
10 / 11 / 2014
Modulation of cutaneous endocannabinoid system by probiotics: implications for keratinocyte survival and immune response Project Objectives To analyze the molecular mechanisms tha...
Concluded
Protein-protein and protein-lipid
10 / 11 / 2014
Protein-protein and protein-lipid interactions: structural triggering of cellular functions Project Objectives To analyze the three-dimensional structure of proteins in solution in the ...
Concluded
Biochemical profiling
10 / 11 / 2014
Biochemical profiling of new chemical entities Project Objectives To profile the specificity of a new class of compounds towards the proteins of the endocannabinoid system. ...
Concluded
Endocannabinoid signalling
10 / 11 / 2014
Emerging role of endocannabinoid signalling in neuropsychiatric disorders Project Objectives To characterize the role of the endocannabinoid system in the onset and progression of neuro...