A double blind randomised controlled tria

Project objectives

The purpose of this study is to investigate whether deep NMB reversed with Sugammadex is superior to moderate NMB reversed with Neostigmine, in terms of overall pain in the first 48 hrs after laparotomic gynecologic surgery, reversal time from NMB (TOF≥0.9) and direct and indirect costs. Additionally we will also assess: drugs consumption for pain and antiemetics (rescue dose), surgical conditions, hemodynamic and respiratory stability, operation time, anesthesia time, total amount and flow rate of CO2, insufflation time, resolution of post-operative ileus, dry mouth and PONV in the first 48 hours, patient satisfaction.

Start/End Date

2018 - 2019

Principal Investigator

Prof. Roberto Angioli – Scientific Coordinator

Prof. Felice Eugenio Agrò

Host Institution

 Campus Bio-Medico University of Rome