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Study of the mechanisms of hepatic fibrogenesis and pathophysiology of the biliary tract aimed at understanding the cellular and molecular basis of liver and biliary tract diseases Project Objectives The focus of the study is on the mechanisms determining fibrogenesis and microvascular remodeling, necrosis, apoptosis, cell regeneration and proliferation in the course of viral and me...

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Study of hepatic expression of Toll-like receptor 4 in chronic liver diseases with viral and metabolic etiology Project Objectives The project aims to study the expression of Toll-like receptor 4 in the liver of patients affected by chronic liver diseases with viral and metabolic etiology. The project is also aimed at understanding the correlation between Toll-like receptor 4 expres...
The study of the expression of inflammatory mediators in the liver and adipose tissue and pathways involved in the progression of tissue and systemic metabolic damage   Project Objectives The project aims to study the expression of the inflammatory mediators and pathways implicated in causing and advancing hepatic damage, and on a more general level, the ongoing systemic ...
The role of the fragile X mental retardation protein in the progression of melanoma: molecular and cellular regulation of metastatic potential   Project Objectives The role of FMRP (the Fragile X Mental Retardation Protein) has been well documented in the brain, where its loss causes Fragile X Syndrome. However, experimental evidence points to an involvement of FMRP in ca...