Alessandro Loppini

DATE OF BIRTH: 9 December 1985

PLACE OF BIRTH: Rome

EDUCATION AND TRAINING

2016 Ph.D. in Biomedical Engineering. UCBM.

2011 Master's Degree in Biomedical Engineering. 110/110 with honors. UCBM.

2017 5th HBP School - Future Medicine. Obergurgl, Austria. November 2017. Human Brain Project Education Programme.

2017 First International Summer Institute on Network Physiology. Como, Italy. July 2017. Lake Como School of Advanced Studies.

2016 XLI Summer School on Mathematical Physics. Ravello, Italy. September 2016. National Institute of Higher Mathematics, National Group for Mathematical Physics (INdAM-GNFM).

2016 XXXIX Summer School on Mathematical Physics. Ravello, Italy. September 2014. National Institute of Higher Mathematics, National Group for Mathematical Physics (INdAM-GNFM).

2013 Applied Bayesian Statistics School. Como, Italy. June 2013. National Research Council, Institute of Applied Mathematics and Information Technologies (CNR IMATI).

2012 Introduction to parallel computing: MPI and OpenMP. Rome Italy. June 2012. Interuniversity Consortium for Supercomputing Applications for University and Research (CASPUR).

PROFESSIONAL CAREER

2023-present Researcher RTD-B in Applied Physics (PHYS-06/A), UCBM.

2018-2023 Researcher RTD-A in Applied Physics (PHYS-06/A), UCBM.

2021-2023 Affiliated Researcher at Center for Life Nano- & Neuro-Science, Istituto Italiano di Tecnologia (IIT).

2016-2018 Postdoctoral researcher, UCBM.

Teaching assignments:

2022-present Professor of General Physics, Biomedical Engineering and Master's Degree Program in Medicine & Surgery MedTech, UCBM.

2019-present Professor of Physics, Master's Degree Program in Medicine & Surgery, UCBM.

2018-present Teacher of Applied Physics, Degree course in Physiotherapy, UCBM.

2023-2026 Teacher of Physiological Models, Master's Degree Program in Medicine & Surgery MedTech, UCBM.

2024-2026 Professor of Applied Physics, Degree Course in Dentistry and Dental Prosthetics, UCBM.

SCIENTIFIC PROJECTS (SELECTED)

2022-ongoing EBRAINS-Italy, CUP B51E22000150006, Funding € 22370240. Role: URT-DSFTM@ unit participantUCBM.

2022-ongoing EC HORIZON-RIA, MUQUABIS, Funding €6700000. Role: unit participant UCBM.

2023-2026 PRIN 20225HYM8N, QUASAR, Funding €23501000. Role: PI unit UCBM.

REVIEWER AND EDITORIAL ROLES

-Associate Editor for Frontiers in Physics (editorial board).

-Academic Editor for PLOS One (editorial board).

CONFERENCES (SELECTED)

-Dynamics Days Europe 2025, Thessaloniki, Greece. “Complex Dynamics in Cardiac Systems”. Speaker and minisymposium organizer.

-Dynamics Days Europe 2024, Bremen, Germany. “Modeling, analysis, and control of cardiac dynamics”. Speaker and minisymposium organizer.

-Dynamics Days Europe 2023, Naples, Italy. “Analysis and control of cardiac dynamics: experiments, modeling, and simulations”. Minisymposium organizer.

-Metrology for Industry 4.0 & IOT 2022. “The Frontiers of Sensing: Quantum & Biosensors”. Special Session organizer.

-DPG Meeting of the Condensed Matter Section (SKM) 2021. “Spatiotemporal correlation of cardiac tissue and its variation in response to temperature”.

-Dynamics Days Europe 2021, Nice, France. “Neuronal dynamics: from single cell up to large-scale networks”. Speaker and minisymposium organizer.

-65th Biophysical Society Annual Meeting, BPS 2021. “Thermo-electric coupling in cardiac dynamics”.

-Modelling the Cardiac Function: Theory, Numerical Methods, Clinical Applications, MCF2020, Poitecnico di Milano, Milan, Italy. “Thermal Effects and Correlation Analysis on Cardiac Tissue”.

-11th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2020, Pisa, Italy. “Temperature effects and correlation analysis in cardiac tissue”.

-PLACE 2019 - Platform of Laboratories for Advances in Cardiac Experience. Confindustria Congress Center, Auditorium della Tecnica, Rome, Italy. 2019. “Experiment, modeling and simulation in cardiac physiopathology”. Symposium organizer.

-XXIV SIBPA National Congress. Marche Polytechnic University, Ancona, Italy. 2018. “Emergent activity of electrically-coupled β-cells: a mathematical modeling approach”.

-9th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2016, Lancaster, UK. “Role of temperature and tissue size on nonlinear cardiac dynamics”.

MEMBERSHIPS

-National Institute of Higher Mathematics, National Group for Mathematical Physics (INdAM-GNFM).

-Italian Society of Pure and Applied Biophysics (SIBPA).

RECENT PUBLICATIONS (SELECTED)

1) Angiolelli, M., Scarpetta, S., Sorrentino, P., Troisi Lopez, E., Quarantelli, M., Granata, C., Sorrentino, G., Palmieri, V., Messuti, G., Stefano, M., Filippi, S., Cherubini, C., Loppini, A., & Chiodo, L. (2025). Role of criticality in the structure-function relationship in the human brain. Physical Review Research, 7(4), 043153.

2) Crispino, A., Nicoletti, M., Loppini, A., Gizzi, A., Chiodo, L., Cherubini, C., & Filippi, S. (2025). Magnetic signature of thermoelectric cardiac dynamics. Physical Review E, 111(1), L012401.

3) Nicoletti, M., Chiodo, L., Loppini, A., Liu, Q., Folli, V., Ruocco, G., & Filippi, S. (2024). Biophysical modeling of the whole-cell dynamics of C. elegans motor and interneurons families. Plos one, 19(3), e0298105.

4) Luchetti, N., Smith, K. M., Matarrese, M. A., Loppini, A., Filippi, S., & Chiodo, L. (2024). A statistical mechanics investigation of unfolded protein response across organisms. Scientific Reports, 14(1), 27658.

5) Luchetti, N., Loppini, A., Matarrese, MA, Chiodo, L., & Filippi, S. (2023). Structural controllability to unveil hidden regulatory mechanisms in unfolded protein response: The role of network models. Physica A: Statistical Mechanics and its Applications, 617, 128671.

6) Luchetti, N., Filippi, S., & Loppini, A. (2023). Multilevel synchronization of human β-cell networks. Frontiers in Network Physiology, 3.

7) Matarrese, M.A., Loppini, A., Nicoletti, M., Filippi, S., & Chiodo, L. (2022). Assessment of tools for RNA secondary structure prediction and extraction: a final-user perspective. Journal of Biomolecular Structure and Dynamics, 1-20.

8) Barone, A., Grieco, D., Gizzi, A., Molinari, L., Zaltieri, M., Massaroni, C., Loppini, A., Schena, E., Bressi, E., de Ruvo, E., Caló, L., & Filippi, S. (2022). A Simulation Study of the Effects of His Bundle Pacing in Left Bundle Branch Block. Medical Engineering & Physics, 107, 103847.

9) Loppini, A., Erhardt, J., Fenton, F.H., Filippi, S., Hörning, M., & Gizzi, A. (2022). Optical Ultrastructure of Large Mammalian Hearts recovers Discordant Alternations by in-silco Data Assimilation. Frontiers in Network Physiology, 17.

10) Scialla, S., Loppini, A., Patriarca, M., Heinsalu, E. Hubs, diversity, and synchronization in FitzHugh-Nagumo oscillator networks: Resonance effects and biophysical implications (2021) Physical Review E, 103 (5), art. No. 052211.

11) Loppini, A., Barone, A., Gizzi, A., Cherubini, C., Fenton, FH, Filippi, S. Thermal effects on cardiac alternans onset and development: A spatiotemporal correlation analysis (2021) Physical Review E, 103 (4), art. No. L040201.

12) Stefano, M., Cordella, F., Loppini, A., Filippi, S., Zollo, L. A Multiscale Approach to Axon and Nerve Stimulation Modeling: A Review (2021) IEEE Transactions on Neural Systems and Rehabilitation Engineering, 29, art. No. 9335942, pp. 397-407.

13) Ruiz-Baier, R., Gizzi, A., Loppini, A., Cherubini, C., Filippi, S. Modeling thermo-electro-mechanical effects in orthotropic cardiac tissue (2020) Communications in Computational Physics, 27 (1), pp. 87-115.

14) Loppini, A., Gizzi, A., Cherubini, C., Cherry, EM, Fenton, FH, Filippi, S. Spatiotemporal correlation uncovers characteristic lengths in cardiac tissue (2019) Physical Review E, 100 (2), art. No. 020201.

15) Nicoletti, M., Loppini, A., Chiodo, L., Folli, V., Ruocco, G., Filippi, S. Biophysical modeling of C. Elegans neurons: Single ion currents and whole-cell dynamics of AWCon and RMD (2019) PLoS ONE, 14 (7), art. No. e0218738.

16) Loppini, A., Filippi, S., Stanley, HE Critical transitions in heterogeneous networks: Loss of low-degree nodes as an early warning signal (2019) Physical Review E, 99 (4), art. No. 040301.