Prof. Antonio Picardi

Born in Casoria (NA) on 1 June 1961, son of Mariano and Maria Teresa Iazzetta.

Degree in Medicine and Surgery, II Faculty of the University of Naples "Federico II", 110/110 cum laude (1987); Specialization in Diseases of the Cardiovascular Apparatus (1990) at the same University. Fellow of the School of Specialization in "Internal Medicine and Hepatology", University Clinic of Navarra, Pamplona, ​​Spain (1989-1994). PhD in "Clinical Pathophysiology" at the same University of Navarra, Pamplona, ​​Spain (1991-1995). Academic activity, Faculty of Medicine and Surgery of the Campus Bio-Medico University, Rome: - Confirmed University Researcher, in the competitive sector 06/B1 - Internal medicine - macro-sector 06/B - General medical clinic (scientific-disciplinary sector MED/09 - Internal Medicine), from November 1999 to today. Assistance activity, with commitment to full-time service, within the Complex Structure of Clinical Medicine, with the task of: -Help from 1 November 1994 to 31 December 2005; -Head of Complex, Verification and Control Functions from 1 January 2006 to 31 May 2009; - Head of the Simple Structure of Hepatology, internal articulation of the Complex Structure of Clinical Medicine, from 1 June 2009 to today. He manages the 10-bed department for RO; Hepatology Day-Hospital and specialist clinics. Among which: Impedancemetry and Skin Plicometry and Nutritional Therapy clinic; Integrated Unit for Hepatocarcinoma Care (UICE) with oncologists, interventional radiologists and general surgeons. Ordinary member of: Italian Society of Internal Medicine (SIMI); American Diabetes Association (ADA); International Association for the Study of the Liver (IASL); The Endocrine Society (ES); European Society for the Study of the Liver (EASL); Italian Society of Gastroenterology (SIGE); Italian Society of Diabetology (SID); Italian Association for Liver Studies (AISF). Reviewer of various international journals.

1: Gallo P, De Vincentis A, Pedone C, Nobili A, Tettamanti M, Gentilucci UV, Picardi A, Mannucci PM, Incalzi RA; REPOSI Investigators. Drug-drug interactions involving CYP3A4 and p-glycoprotein in hospitalized elderly patients. Eur J Intern Med. 2019 Jul;65:51-57. doi: 10.1016/j.ejim.2019.05.002. Epub 2019 May 10. PubMed PMID: 31084979.

2: De Vincentis A, Costanzo L, Vespasiani-Gentilucci U, Picardi A, Bandinelli S, Ferrucci L, Antonelli Incalzi R, Pedone C. Association between non-invasive liver fibrosis scores and occurrence of adverse health outcomes in older people. Dig Liver Dis. 2019 Feb 3. pii: S1590-8658(19)30052-0. doi: 10.1016/j.dld.2019.01.017. [Epub ahead of print] PubMed PMID: 30808572.

3: Vespasiani-Gentilucci U, Gallo P, Dell'Unto C, Volpentesta M, Antonelli-Incalzi R, Picardi A. Promoting genetics in non-alcoholic fatty liver

disease: Combined risk score through polymorphisms and clinical variables. World J Gastroenterol. 2018 Nov 21;24(43):4835-4845. doi:10.3748/wjg.v24.i43.4835. PubMed PMID: 30487694; PubMed Central PMCID: PMC6250919.

4: Masetti C, Lionetti R, Lupo M, Siciliano M, Giannelli V, Ponziani FR, Teti E, Dell'Unto C, Francioso S, Brega A, Montalbano M, Visco-Comandini U, Taibi C, Galati G, Vespasiani Gentilucci U, Picardi A, Andreoni M, Pompili M, Pellicelli AM, D'Offizi G, Gasbarrini A, De Santis A, Angelico M. Lack of reduction in serum alpha-fetoprotein during treatment with direct antiviral agents predicts hepatocellular carcinoma development in a large cohort of patients with hepatitis C virus-related cirrhosis. J Viral Hepat. 2018 Dec;25(12):1493-1500. doi:

10.1111/jvh.12982. Epub 2018 Sep 6. PubMed PMID: 30112854.

5: Vespasiani-Gentilucci U, Dell'Unto C, De Vincentis A, Baiocchini A, Delle Monache M, Cecere R, Pellicelli AM, Giannelli V, Carotti S, Galati G, Gallo P, Valentini F, Del Nonno F, Rosati D , Morini S, Antonelli-Incalzi R, Picardi A. Combining Genetic Variants to Improve Risk Prediction for NAFLD and Its Progression to Cirrhosis: A Proof of Concept Study. Can J Gastroenterol Hepatol. 2018 Mar 14;2018:7564835. doi:10.1155/2018/7564835. eCollection 2018. PubMed PMID: 29732362; PubMed Central PMCID: PMC5872672.

6: Vespasiani-Gentilucci U, Gallo P, Picardi A. The role of intestinal microbiota in the pathogenesis of NAFLD: starting points for intervention. Arch Med Sci. 2018 Apr;14(3):701-706. doi: 10.5114/aoms.2016.58831. Epub 2016 Mar 23. PubMed PMID: 29765460; PubMed Central PMCID: PMC5949899.

7: Gallo P, De Vincentis A, Pedone C, Nobili A, Tettamanti M, Vespasiani Gentilucci U, Picardi A, Mannucci PM, Incalzi RA; REPOSI Investigators. Prognostic relevance of glomerular filtration rate estimation obtained through different equations in hospitalized elderly patients. Eur J Intern Med. 2018 Aug;54:60-64. doi: 10.1016/j.ejim.2018.04.001. Epub 2018 Apr 9. PubMed PMID: 29650358.

8: Vespasiani-Gentilucci U, Vorini F, Carotti S, De Vincentis A, Galati G, Gallo P, Scopinaro N, Picardi A. Hepatic complications of bariatric surgery: the reverse side of the coin. Acta Gastroenterol Belg. 2017 Oct-Dec;80(4):505-513. Review. PubMed PMID: 29560647.

9: Basili S, Raparelli V, Napoleone L, Talerico G, Corazza GR, Perticone F, Sacerdoti D, Andriulli A, Licata A, Pietrangelo A, Picardi A, Raimondo G, Violi F; PRO-LIVER Collaborators. Platelet Count Does Not Predict Bleeding in Cirrhotic Patients: Results from the PRO-LIVER Study. Am J Gastroenterol. 2018 Mar;113(3):368-375. doi: 10.1038/ajg.2017.457. Epub 2017 Dec 19. PubMed PMID: 29257146.

10: Carotti S, Guarino MPL, Valentini F, Porzio S, Vespasiani-Gentilucci U, Perrone G, Zingariello M, Gallo P, Cicala M, Picardi A, Morini S. Impairment of GH/IGF-1 Axis in the Liver of Patients with HCV-Related Chronic Hepatitis. Horm Metab Res. 2018 Feb;50(2):145-151. doi: 10.1055/s-0043-118911. Epub 2017 Sep 18. PubMed PMID: 28922679.