Prof. Simone Carotti

Associate of Human Anatomy, he has been present at the Bio-Medico Campus as a lecturer since 2008 and is responsible for the Microscopic and Ultrastructural Anatomy Unit carrying out histomorphological and molecular research activities in the field of the study of organ fibrosis with particular interest in hepatic fibrosis, with a scientific production characterized by numerous experimental and review works published in the most important international journals in the sector.

since 2022: member of the Italian Society of Pathological Anatomy

since 2021: Member of the Editorial Board of Journal of Physiology and Biochemistry, Springer Nature Ed and Academic Editor of Cells, MDPI Journals.

from 2020: assistance assignment at the UOS of Predictive Molecular Diagnostics of the Campus Bio-Medico Polyclinic Foundation in Rome.

Since 2018: Coordinator of Personal Tutoring at the Departmental Faculty of Medicine and Surgery of theUniversità Campus Bio-Medico di Roma

since 2018: member of the Teaching Staff of the Doctoral School in Biomedical Sciences and Bioethics of theUniversità Campus Bio-Medico di Roma.

since 2018: Associate Professor in Human Anatomy (BIO16), Università Campus Bio-Medico di Roma where he holds various teaching positions in Anatomy in the Degree Courses of Medicine and Surgery, Food Sciences and Human Nutrition, Industrial Engineering, Nursing, Physiotherapy, Medical Radiology Techniques for Imaging and Radiotherapy.

since 2008: member of the Italian Society of Anatomy and Histology

2007: PhD in "Experimental and Clinical Hepatology", University "La Sapienza" of Rome

2007: admitted to the School of Specialization in Pathological Anatomy, Università Campus Bio-Medico di Roma

2003: Degree in Medicine and Surgery, Università Campus Bio-Medico di Roma with a grade of 110/110 and honors; qualification for the medical-surgical profession

1. Tavaglione F, Jamialahmadi O et al. Development and Validation of a Score for Fibrotic Nonalcoholic Steatohepatitis. Clin Gastroenterol Hepatol. 2022 Apr 11:S1542-3565(22)00385-8.

2. Valentini F, Rocchi G et al. The Origins of NAFLD: The Potential Implication of Intrauterine Life and Early Postnatal Period. Cells. 2022 Feb 5;11(3):562.

3. Tavaglione F, De Vincentis A et al. Accuracy of controlled attenuation parameter for assessing liver steatosis in individuals with morbid obesity before bariatric surgery. Liver Int. 2022 Feb;42(2):374-383.

4. Carotti S, Lettieri-Barbato D et al. Molecular and histological traits of reduced lysosomal acid lipase activity in the fatty liver. Cell Death Dis. 2021 Nov 18;12(12):1092.

5. Ferri F, Carotti S et al. The Propensity of the Human Liver to Form Large Lipid Droplets Is Associated with PNPLA3 Polymorphism, Reduced INSIG1 and NPC1L1 Expression and Increased Fibrogenetic Capacity. Int J Mol Sci. 2021 Jun 5;22(11):6100.

6. Carotti S, Zingariello M et al. Fragile X mental retardation protein in intrahepatic cholangiocarcinoma: regulating the cancer cell behavior plasticity at the leading edge. Oncogene. 2021 Jun;40(23):4033-4049.

7. Colyn L, Bárcena-Varela M et al. Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma. Hepatology. 2021 Jun;73(6):2380-2396.

8. Carotti S, Aquilano K et al. An overview of deregulated lipid metabolism in nonalcoholic fatty liver disease with special focus on lysosomal acid lipase. Am J Physiol Gastrointest Liver Physiol. 2020 Oct 1;319(4):G469-G480.

9. Carotti S, Aquilano K et al. Lipophagy impairment is associated with disease progression in NAFLD. Front Physiol. 2020 Jul 17;11:850.

10. Turchi R, Tortolici F et al. Frataxin deficiency induces lipid accumulation and affects thermogenesis in brown adipose tissue. Cell Death Dis. 2020 Jan 23;11(1):51.

11. Secret F, Carotti S et al. The role of angiogenesis, inflammation and estrogen receptors in breast implant capsules development and remodeling. J Plast Reconstr Aesthet Surg. 2018 May;71(5):637-643.

12. Carotti S, Guarino MPL et al. Impairment of GH/IGF-1 Axis in the Liver of Patients with HCV-Related Chronic Hepatitis. Horm Metab Res. 2018 Feb;50(2):145-151.