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In vitro characterization of MAGL inhibitors

 

Project objectives

The project aims to test the ability of different chemical compounds to inhibit monoacyl glycerol lipase (MAGL), the enzyme responsible for regulating the production of inflammatory mediators derived from arachidonic acid and the endocannabinoid 2-arachidonoylglycerol.

Start and end date

2018 - 2019

Project Manager

Prof. Mauro Maccarrone 

Coordinating institution of the project

Università Campus Bio-Medico di Roma

Other Institutions involved

University of Rome "Tor Vergata"

Funding source(s).

Hoffmann - La Roche Ltd. (Switzerland)

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