Comparison between the two different quantitative HCV RNA assays COBAS AmpliPrep/COBAS TaqMan HCV and VERSANT HCV RNA Assay (kPCR) system in evaluating low viral load in HCV infection
Project objectives
To evaluate the different sensitivities of molecular methods for the detection of HCV RNA, especially in relation to HCV RNA titers below the sensitivity limits of the different assays. The aim of the study is to evaluate whether low viral loads (observed with some tests but not with others) can predict HCV RNA rebound (relapsers) during or after treatment in patients with chronic type C infection.
Start and end date
2014 - 2015
Project Manager
prof Elisabetta Riva
Coordinating institutions of the project
- Università Campus Bio-Medico di Roma
- Sapienza University of Rome
Source of funding
Prof. Funds Guido Antonelli, Sapienza University of Rome