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REPORT

Management of primary biliary cirrhosis and treatment with obeticholic acid in a large real-world series.

Project objectives

The objectives of the projects are attributable to the fields of interest of the UDR of Clinical Medicine and Hepatology:

1. Innovative treatments of advanced metabolic liver disease (MAFLD/NASH) with international multicenter intervention trials; 2. Innovative treatments of Primary Biliary Cholangitis (PBC);

3. Scouting and characterization of MAFLD/NASH and risk factors for the evolution of chronic liver disease, including any genetic predispositions;

4. Scouting for cases of chronic Hepatitis C Virus (HCV) infection that are currently susceptible to effective and well-tolerated treatment, even in elderly patients or with advanced liver disease;

5. Characterization and innovative treatments of sarcopenia in advanced chronic liver disease or malignancy;

6. Characterization of malignant and benign hepatic nodules using non-invasive techniques of temporary elastometry.

Start and end date

July 2020 - Completed in 2023

Project Manager

Vespasiani - Principal Investigator

Coordinating institution of the project

UCBM
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