Ross operation

Project objectives

In an attempt to contain the inevitable dilation of the pulmonary autograft after Ross surgery, numerous conduit reinforcement strategies have been proposed over the years. However, at the current stage of research, there is no preclinical model evaluating the Ross procedure in large animals in an attempt to understand the pathophysiological basis of dilation and the efficacy of reinforcement techniques during growth. The aim of this research is to develop a clinical model of Ross surgery in large animals, in order to reproduce the clinical scenario in which the procedure can be applied and to allow the development and evaluation of the various technologies available for improving the performance of the pulmonary autograft. In this context, the objective of the research unit is to test a bioabsorbable mesh, produced in collaboration with the Department of Bioengineering at the University of Bologna.Università Campus Bio-Medico di Roma, for the strengthening of the pulmonary artery autograft.

Start and end date

January 2014 - December 2015

Project Manager

Prof. Massimo Chello – Extraordinary Professor

Coordinating institution of the project

Center Cardiologique du Nord de Saint-Denis - Paris, FRANCE

Other Institutions involved

• Università Campus Bio-Medico di Roma

• Department of Cardiothoracic Surgery, Golden Jubilee National Hospital, Clydebank, Glasgow, United Kingdom

Funding source(s).

Center Cardiologique du Nord de Saint-Denis - Paris, FRANCE