Development of a systemic sclerosis skin tissue model via 3D bioprinting for investigating novel potential therapeutic treatments

Project objectives

• Design and analysis of a scleroderma skin prototype by 3D bioprinting using dermal cells (fibroblasts and keratinocytes) isolated from patients suffering from systemic sclerosis.
• Use of the scleroderma skin model as a platform for studying the molecular mechanisms associated with Systemic Sclerosis and development/analysis of the effect of new drugs.

Start and end date

Project Manager

Coordinating institution of the project

Other Institutions involved

• 3D Bioprinting Lab, Institute of Biochemistry and Cell Biology (IBBC) — National Research Council (CNR)
• Tissue Engineering Laboratory, Department of Engineering, Università Campus Bio-Medico di Roma