Identification of molecular and cellular profiles predictive of efficacy to immunotherapies in advanced solid tumors

Project objectives

• analyze whether the presence of specific microRNA profiles associated with microvesicles are able to predict the efficacy and toxicity of immunotherapies
• evaluate whether specific immune cellular profiles are able to predict the efficacy and toxicity of immunotherapies

Start and end date

Project Manager

Coordinating institution of the project

Other Institutions involved

• Department of Molecular Biological Sciences and Swiss Institute of Bioinformatics, University of Zurich 
• Department of Experimental Medicine, La Sapienza University of Rome
• Department of Clinical Sciences and Translational Medicine, University of Rome “Tor Vergata”, 
• Clinical Pharmacology and Pharmacogenetics Unit, University of Pisa