Multicenter, randomized, controlled, tri-group, parallel phase III study to determine the efficacy and safety of lenalidomide in combination with dexamethasone (RD) versus lenalidom # 3BB6394.
Project Objectives
Primary objectives:
- To evaluate the efficacy of RD combination compared with MPR and CPR in elderly patients with newly diagnosed symptomatic multiple myeloma.
- To evaluate the efficacy of lenalidomide treatment as a maintenance therapy (in combination with prednisone) after the induction phase.
Secondary objectives:
- To evaluate the safety of RD combination compared with MPR and CPR in patients with newly diagnosed symptomatic multiple myeloma
- To evaluate the safety of lenalidomide as a maintenance therapy after the induction phase
Start/End Date
November 29, 2010 - closed
Principal Investigator
Prof. Giuseppe Avvisati
Host Institution
Università di Torino, A.O.U. S. Giovanni Battista di Torino, Division of Hematology - Turin, Italy
Other Institutions involved
Institutions included in the “Gruppo Italiano Malattie Ematologiche dell’Adulto (GIMEMA)”
Source of funding
Fondazione Neoplasie Sangue Onlus (FO.NE.SA Onlus)