Mouse models of myelofibrosis

Project objectives

The aim of this project is to use the Gata1low mouse model to identify in detail the patho-biological mechanism that determines the mobilization of stem/progenitor cells and extramedullary hematopoiesis in primary myelofibrosis.

Start and end date

Project Manager

Coordinating institution of the project

Other institutions involved in the project

• Anna Rita Franco Migliaccio, Lecce, Italy
• John A. Stamatoyannopoulos, Altius Institute for Biomedical Sciences, Seattle, WA, USA
• John Crispino, St. Jude Children's Research Hospital, Memphis, TN, USA
• Ronald Hoffman, Icahn School of Medicine at Mount Sinai, New York, NY, USA
• John Mascarenhas, Icahn School of Medicine at Mount Sinai, New York, NY, USA
• Ross Levine, Memorial Sloan Kettering Cancer Center New York, NY

Funding source(s).