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NERONE - NERd Open study on real resistaNcE to PPI

Prospective, multicenter, open-label study of patients with non-erosive gastroesophageal reflux disease (NERD) who are non-responders to proton pump inhibitor therapy

Project objectives

Prevalence assessment - checked for compliance, timing, type and dose of Proton Pump Inhibitors and measured prospectively - of patients suffering from non-erosive gastro-oesophageal reflux disease resistant or poorly sensitive to treatment with gastroprotectors administered for 8 weeks.

Start and end date

2017 - ongoing

Project Manager

Prof. Michele Cicala, Dr. Mentore Ribolsi

Coordinating institution of the project

Complex Gastroenterology Operational Unit, Università Campus Bio-Medico di Roma

Other Institutions involved

  • Gastroenterology and Endoscopy Unit, IRCCS Ca' Granda Foundation Ospedale Maggiore Policlinico, University of Milan
  • Gastroenterology Unit, University of Genoa
  • Division of Internal Medicine, University "G. D'Annunzio", Chieti
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