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Preclinical study in the Gata1low mouse model of the mechanism of action of Reparixin in the reversal of pulmonary fibrosis.

Project objectives

Evaluation of the effect of Reparixin on pathological emperipolesis between megakaryocytes and neutrophils in the etiopathology of pulmonary fibrosis of the Gata1low model.

Start and end date

2023 - 2025

Project Manager

prof Anna Rita Franco Migliaccio

Coordinating institution of the project

Università Campus Bio-Medico di Roma

Other institutions involved in the project

  • Istituto Superiore di Sanità (ISS), Rome, Italy
  • Luca Richeldi, Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Catholic University of the Sacred Heart, Rome
  • Giuseppe Sarli, Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia (Bologna)

Funding source(s).

Dompé farmaceutici SpA, Milan, Italy
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