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Preclinical study in the Gata1low mouse model of the mechanism of action of Reparixin in the reversal of pulmonary fibrosis.
Project objectives
Evaluation of the effect of Reparixin on pathological emperipolesis between megakaryocytes and neutrophils in the etiopathology of pulmonary fibrosis of the Gata1low model.
Start and end date
2023 - 2025
Project Manager
prof Anna Rita Franco Migliaccio
Coordinating institution of the project
Università Campus Bio-Medico di Roma
Other institutions involved in the project
Istituto Superiore di Sanità (ISS), Rome, Italy
Luca Richeldi, Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Catholic University of the Sacred Heart, Rome
Giuseppe Sarli, Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia (Bologna)