PRP application after arthroscopic rotator cuff repair
Project objectives
There is a lack of Level I studies on the therapeutic efficacy of PRP preparations to improve tendon healing and clinical performance of the shoulder in patients undergoing arthroscopic rotator cuff repair. Several studies and research have shown that the best healing depends on the dosage of the cytokines, the timing, and the vehicle used. It is unlikely that a single factor will have a major effect when used in isolation. Numerous factors (such as PRP) have been reported to produce the desired clinical effects, if maintained at high concentrations from the day after surgery. To achieve the goal we chose intra-articular injections of PRP performed one two and three weeks after surgery. Indeed, we want to test the null hypothesis that there is no statistically significant difference regarding Constant, UCLA and VAS score in the preoperative and postoperative phases in a group (PRP group) of patients treated with arthroscopic repair and three consecutive intra-articular PRP injections versus a group of patients treated by arthroscopic repair alone (control group).
Start and end date
2011 - 2013
Project managers
- Prof. Vincenzo Denaro
- Prof. Rocco Papalia
- Dr. Francesco Franceschi
Coordinating institution of the project
Università Campus Bio-Medico di Roma
Funding source
ACP - ARTHREX, NAPLES, FLORIDA, USA