Research areas and methodologies

The Virology Research Unit is mainly involved in both Basic and Clinical Virology. The lines of research concern viral and host factors capable of influencing the clinical course and/or the response to treatment of some viral infections. The viral infections under study are in particular HCV infection (in terms of progression and response to treatment); HPV infection (in terms of lesion progression); CMV infection (in terms of clinical course and reactivation) in haematological transplanted patients and in immunocompromised subjects; Respiratory tract infections in immunocompromised. The Virology Unit has advanced molecular methods that allow the qualitative/quantitative molecular study of viral genomes as well as single nucleotide polymorphisms (SNP) via Real Time PCR and sequencing. Syndromic molecular panels are also available for studying respiratory tract and central nervous system infections. It has also dealt with the molecular diagnostics of SARS CoV and the sequencing of the variants of SARS CoV, still active in collaboration with INMI and ISS.
The Virology Unit has advanced molecular methods that allow the qualitative/quantitative molecular study of viral genomes as well as polymorphisms asinghol nucleotide (SNP) via Real Time PCR. Syndromic molecular panels are also available for the study of respiratory tract and central nervous system infections.
It has also dealt with the molecular diagnostics of SARS CoV2 and the sequencing of the variants of SARS CoV2, still active in collaboration with INMI and ISS.

Research projects in progress

  • Comparison of Syndromic Molecular Panels in the Monitoring of Respiratory Infections in Pediatric Patients;
  • Viral Infections in Migrants;
  • Monitoring of viral infections in immunocompromised patients and in IBD;
  • Study of the Virobiota in hematological subject

Collaborations with other research centres

  • INMI Spallanzani, Rome
  • ISS, Rome
  • Virology Sapienza University of Rome