Isaia Barbieri

Research group leader in the Department of Pathology at the University of Cambridge

ib318@cam.ac.uk

Isaia Barbieri Ph.D. obtained his master degree in biotechnology at the University of Turin in 2008 and his doctoral degree in molecular biotechnology at the University of Turin in 2012.

 

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Isaia completed his Ph. D. training in the Molecular Biotechnology Center at the University of Turin, working on signaling pathways involved in the pathogenesis of Her2 positive breast cancer.
He then moved to the University of Cambridge for his post-doctoral training and worked in the Laboratory of Professor Tony Kouzarides at the Gurdon Institute.
Initially his interests were the epigenetic mechanisms involved in the pathogenesis of blood cancer and specifically he characterizing the inhibition of BET proteins in Myeloproliferative neoplasms.  More recently he switched his interests to the field of epitranscriptomic with a focus on studying the role of m6A (6-methyladenosine) RNA methylation in acute myeloid leukaemia.
Finally, he focused his attention in studying the roles of a different RNA methylation (7-methylguanosine) in lung cancer cellular models.

Research interest

In 2018 Isaia Started his independent research group in the department of pathology, further studying epigenetic and epitranscriptomic mechanisms in cancer cellular models. In particular, the laboratory is interested in studying the interplay between epigenetic and epitranscriptomic modifications of DNA and RNA and identify potential candidates for new cancer treatment.

Donato Bini

Senior researcher, Istituto per le applicazioni del cacolo M.Picone CNR

donato.bini@gmail.com

Dr. Donato Bini graduated in Physics at the University of Rome “Sapienza” in 1989, with the highest grades. At “Sapienza” he also obtained his PhD in Physics in 1995. From 1995 to 1998 he had  a temporary position at the CNR “Istituto per le Applicazione della Matematica” in Naples (IT).

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From 1998 he has a permanent position as a Researcher at the CNR, Istituto per le Applicazioni del Calcolo “M. Picone” Rome (IT), where he is still now in  a Senior Researcher position. He has been the principal investigator  of two research projects of  INDAM (the  Italian National Institute of High Mathematics) on the topic of relativist global position systems and the leader of a CNR joint collaboration project with Venezuela.  Since 2004 he is a contract Professor with the University Campus Bio-Medico in Rome and since 2011 he is a Visiting Professor at the “Institut des Hautes Études Scientifiques” in Paris (FR). He acts as a reviewer for many scientific journals (he has been recognized as Outstanding Reviewer by the IOP journal “Classical and Quantum Gravity” in the years 2017 and 2018).

Research interest

The main topic of  Donato Bini’s  interest is general relativity with special attention to several classical aspects of the theory, like the analysis and the interpretation of  exact solutions of  Einstein’s field equations. In particular, he is interested in  spacetime splitting techniques, the measurement process and the role of the observer in general relativity, particle dynamics in certain fixed gravitational backgrounds, gravitational perturbations, and gravitational waves. Currently, his research activities involve applications of the post-Newtonian approximation of general relativity, gravitational self-force, and the effective-one-body model for the description of the dynamics of  binary systems.

He is an expert user of the Maple™ tensor calculus package and the author of about 200 peer-reviewed papers and 2 books.

Dennis Black

Full Professor of Epidemiology and Biostatistics, Head of Division of Chronic Diseases, UC, University of Florida, San Francisco

dblack@psg.ucsf.edu

Dr. Black has over 20 years of experience investigating osteoporosis and therapies to treat this disease. His most recent research involved the evaluation of treatments for osteoporosis and the risk of fracture.

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The study concluded that benefits of treatments outweigh the risk of rare femoral fractures. The results were published in early 2010 in the New England Journal of Medicine and received extensive media coverage. Dr. Black is currently Principal Investigator, along with Dr. Roberta Ballard, for a multi-center trial (TOLSURF) pioneering treatment for BPD (bronchopulmonary dysplasia) for extremely low birth weight infants.

Research Interests

  • Osteoporosis
  • Clinical trials
  • He has published over 200 peer reviews articles.

Jack Harry Brelstaff

Senior Research Associate in the department of Clinical Neuroscience

jb961@cam.ac.uk

Dr Jack Brelstaff graduated with a first class hons B.S.c from Queen Mary University of London in Biomedical Sciences, Distinction M.S.c from King’s College London in Neuroscience, and attained his PhD from University College London in Neurodegeneration. During his post-doctoral appointments at the University of Cambridge, he was awarded a Junior Fellowship from Alzheimer’s Research UK and taught Physiology at Clare College Cambridge.

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In addition to his research interests Dr Brelstaff has taught Pysiology to first-year undergraduate students at the University of Cambridge in small group supervisions. He has also given guest lectures at the Polytecnico de Torino (Italy) on Neuroscience and Neurodegeneration to third-year Biomedical Engineering students. He has recently completed the Teaching Associates Program at the University of Cambridge for admission to the Higher Education Academy at the level of Fellow. He sits as a Review Editor at the journals Frontiers in Molecular Neuroscience and Frontiers in Cellular Neuropathology, as well as publishing high impact papers most recently in Cell Reports and Science Advances.

Research interest

Dr Brelstaff’s research focuses on the mechanisms of cell death in neurodegenerative disease. Whilst it is well known that neurons die during Alzheimer’s disease and related dementias’, the mechanism of cell death is poorly understood. Inflammation is a common feature of all neurodegenerative diseases and could drive many different cell death mechanisms, as well as causing early deficits in neuronal function. His research has shown that neurons with pathological protein aggregates of tau expose phagocytic signals that trigger microglia to kill them by phagocytosis. This process alters the phagocytic microglial cells to drive inflammation and seed more aggregates of tau, thereby driving the disease forward.

Michael Brook

Professor of Pediatrics, University of California San Francisco

michael.brook@ucsf.edu

Director of Pediatric Echocardiography, University of California-San Francisco

Medical Director of Information Technology and Clinical Services, Pediatric Heart Center, University of California

Asssociate Program Director, Pediatric Cardiology Fellowship Program

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I have been a Pediatric Cardiologist for 30 years and specialize in Echocardiography in children and adults with congenital heart disease. I have been the Director of the Echocardiography Program at UCSF since 2002. For 17 years I was also the Director of the Pediatric Cardiology Fellowship Training Program. I have worked around the world, including in Italy, Cambodia, Zambia and been a speaker on cardiology in the United States and Internationally.

Research interest

My academic interests are generally in the diagnosis of congenital heart disease using echo, particularly in improving diagnostic quality and reducing errors in preoperative diagnosis. I have a particular interest in databases and in structured reporting, specifically using measurement data to drive diagnostic interpretation directly to remove subjectivity and variability.

Luca Borghi

Head of Department of FAST (Institute of Philosophy of Scientific and Technological Practice), Assistant professor of History of Medicine, Università Campus Bio-Medico di Roma

l.borghi@unicampus.it

Luca Borghi (Bologna, 1962) teaches History of Medicine and History of Science at the University Campus Bio-Medico in Rome, Italy. He is Head of Department of FAST (Institute of Philosophy of Scientific and Technological Practice) of the same University.

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He is a member of the Italian Society for the History of Medicine, coordinator of its Research group about the Italian anatomical theatres (THESA) and co-editor of the Society’s journal Medicina Historica. Since January 2017, he is the Italian National Delegate of the International Society for the History of Medicine; since January 2019 he is the Editor of the International Society’s quarterly Newsletter.

 

Research Interests

His research interests and activities are mainly focused on the “human factor” of medical evolution in the 19th and early 20th centuries and on the material traces left by the history of healthcare. He promoted and coordinates project "Himetop - The History of Medicine Topographic Database "(himetop.net), an international on-line database, which aims to locate, describe and valorise the places of medical and health history, such as ancient hospitals, monuments, birthplaces and tombs of relevant physicians, specialized museums and libraries. His more recent books are a biography of 19th century Italian clinician and statesman, Guido Baccelli, and a history of the Italian paediatric hospital “Giannina Gaslini” in Genoa. He is about to publish a monograph on “William Osler and Italy”. He recently started a biographical research about Sir Aldo Castellani.

Massimo Ciccozzi

Associate Professor of Medical Statistics, Università Campus Bio-Medico di Roma

m.ciccozzi@unicampus.it

Prof. Massimo Ciccozzi obtained a degree in Biological science and a master’s degree in epidemiology and biostatistics, a graduation in molecular Biology (Catholic University of Rome), a graduation in epidemiology and Biostatistics (Johns Hopkins University Baltimore).

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Worked as researcher since 1990 at the National Institute of Health in Rome and is now Associate Professor and director of the Medical Statistic and Molecular Epidemiology Unit at the Campus Bio-Medico University in Rome. He is a consultant epidemiology for WHO in different countries. He made Studies on field epidemiology and surveillance systems and molecular epidemiology.

Research interests

He is expert in phylogenetic and evolutionary analysis of microorganism and infectious diseases. These studies has been also conducted in several countries where Prof Ciccozzi has been named as expert consultant (Albania, Montenegro, Bulgaria, Egypt, Turkey, USA). He has been the Principal Investigator in many National and international project on AIDS. He is epidemiologist expert in Molecular epidemiology, Surveillance System of infectious diseases and global health. He is author of more than 350 international publications, editor and reviewer for many journals.

Gianmarco Contino

Associate Professor of Cancer Genomic Medicine and Honorary UpperGI Surgery Consultant at the University of Birmingham

g.contino@bham.ac.uk

Gianmarco is an Associate Professor of Cancer Genomic Medicine and Honorary Consultant of Upper Gastrointestinal Surgery at the University of Birmingham and research associate of the Von-Hugel Institute at the University of Cambridge. Previously he was a Clinical lecturer at the University of Cambridge and Addenbrooke’s Hospital. He trained as a surgical oncologist and translational scientist in several institutions including the European Institute of Oncology (Milan), Harvard Medical School and Mass General Hospital (Boston), University of Illinois at Chicago and Imperial College (London).

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He is the head of the Cancer Structural Variation and Aneuploidy Research Lab (c-StAR) of the Institute of Cancer and Genomic Sciences at the University of Birmigham where his research focuses on cancer genomic of Barrett’s oesophagus and oesophageal adenocarcinoma, personalised oncology and AI algorithms to improve therapeutic strategies for cancer therapies. His clinical expertise focuses on interventional endoscopic treatment of early upper gastrointestinal cancers. Gianmarco also serves as Network Relation Chair of the Pathobiology group of the European Organization for Research and Treatment of Cancer (EORTC). He published extensively on molecular biology and cancer genomics of Pancreatic and Oesophageal Adenocarcinoma. His research has been supported by American Italian Cancer Foundation, the Associazione Italiana per la Ricerca sul Cancro, Fondazione Umberto Veronesi, the National Institute for Health Research and the Imperial College NHS foundation.

Marcello D'Amelio

Full Professor of Human Physiology Università Campus Bio-Medico di Roma

m.damelio@unicampus.it

Marcello D’Amelio, Dr. Neuroscience and M.Sc. in Clinical Experimentation, is Professor of Human Physiology and Coordinator of the integrated course, Fundamentals of Medicine II, in MD Master Degree Program at the School of Medicine, Campus Bio-Medico University of Rome.

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In January 2011, I was appointed as Director of the Laboratory of Molecular Neuroscience at European Centre for Brain Research, Santa Lucia Foundation, Rome, Italy. Since January 2012, I serve, as Director of the Molecular Neuroscience Unit at Medical School University Campus Bio-medico in Rome, where I has been appointed as Full Professor.

I has been awarded the “2013 Bioeconomy Rome, International Prize” for outstanding contributions of young Italian scientist in the field of translational research in neurodegeneration,  and “2015 Raffaele Giuliano Prize” for the quality and originality of the scientific production".

I am supported by Alzheimer's Association's (USA), by the Italian Ministry of Health, and by Farmindustria.

For a full list of scientific publications please check https://orcid.org/0000-0001-6526-1832

Research Interests

I am interested in the cellular and molecular mechanisms that underlie long-lasting changes of synaptic function in both normal, healthy brains and in the brains of those affected by neurological disorders, in particular Alzheimer's Disease (AD) and Parkinson’s Disease (PD). A plethora of techniques is employed, including chemical biology, molecular biology, patch-clamp electrophysiology, calcium imaging, and neurobehavioral paradigms.

Luca Facchinelli

Programme Manager/Vector Biologist at Liverpool School of Tropical Medicine

luca.facchinelli@Istmed.ac.uk

I am a Medical Entomologist specialized in mosquito ecology and behaviour. I have experience in mosquito surveillance, large cage studies, and in managing the transition of transgenic mosquitoes from the laboratory to the field. Currently, I focus my research on revealing the domestic behaviour of Aedes aegypti, the most important vector of arboviruses to humans, by using a video tracking system. Indoor mosquito movements and resting positions can be exploited to target control interventions based on insecticide use.

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My Ph.D. project at University of Rome Sapienza (Public Health and Microbiology Department), focussed on the development and field-testing of a sticky trap for collecting Stegomyia adults, monitor their population dynamics, and study their biology. I have a postdoctoral experience of nine years, eight of which spent in FNIH, Bill & Melinda Gates Foundation funded projects at University of California, Davis, and at University of Perugia, Italy. In the frame of these projects, I worked both in large cages and in the field to evaluate the performances of wild type and transgenic dengue and malaria vectors with the aim of moving to the field transgenic lines for controlling mosquito-borne diseases.

Giampaolo Ghilardi

Assistant Professor of FAST (Institute of Philosophy of Scientific and Technological Acting, Università Campus Bio-Medico

g.ghilardi@unicampus.it

 

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Graduated summa cum laude in Philosophy in 2002 at the Università Cattolica of Milan where he obtained the Teaching Qualification in Philosophy and Human Science in 2004, Phd in Bioethics in 2011 at the Università Campus Bio-medico Rome. After 4 years of post-doctoral fellowship in the same University he was appointed Assistant Professor in Moral Philosophy in 2017.
He got the Associate Professor habilitation in 2018.
Member of the Institute of Philosophy of Scientific and Technological Acting, Italian Society of Moral Philosophy, Interdisciplinary Group of Clinical Bioethics and Ethical Consulting in Health Care, Sciences Literature and Arts Academy of Bergamo (moral sciences section), in 2018 he won the Michele Erede Prize with a paper on Precision Medicine.

Research interest

His main interest field is Science Ethics. He devoted several years working on the ethics, anthropology, and epistemology underlying Neurosciences, in particular focusing on free will, ethical dilemmas stemming from neuroscientific approaches, and medical practice. He studied clinical methodology both from the ethical and epistemological perspective, focusing on different steps of clinical reasoning and its logic. He later developed this stream of inquire into the Ethics of scientific and technological acting. His publications (more than 40 and three books) deals with ethical and anthropological issues in Bioethics, Neuroethics, Roboethics, Ethics applied to Medicine, Medicine and Rhetoric, Precision and Personalized Medicine, Medical Humanities. He coauthored two papers on Leonardo da Vinci published by The Lancet (2017, 2019) on the epistemological and ethical issues in Leonardo’s anatomical drawings.

Peter Kreuzaler

Postdoc in Dr Mariia Yuneva’s group at the Francis Crick Institute in London

peter.kreuzaler@crick.ac.uk

Peter Kreuzaler obtained his undergraduate degree in biochemistry from the Free University of Berlin in 2007, and subsequently moved to the University of Cambridge, where he was awarded his PhD in 2011. He then joined Professor Gerard Evan’s group at the University of Cambridge as a postdoctoral research fellow (2012-2017), and currently works at the Francis Crick Institute in London conducting further postdoctoral research in Dr Mariia Yuneva’s group.

 

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He has been lecturing at the University of Cambridge in the fields of molecular biology, cell death, and cancer for a number of years. He ha salso pursued his passion for teaching through the supervision of PhD students and Master students. Throughout his career, he has received numerous Fellowships, most notably a Junior Research Fellowship at Trinity College Cambridge.

Research interest

His research has spanned various fields of molecular and cancer biology. During his PhD Dr Kreuzaler identified a novel pathway of cell death as the driving force behind the physiological process of post-lactational mammary gland involution. He then moved into the study of breast cancer, where he found that different clones of cancer can complement each other’s signalling, thus building a synergy between them. His current works focus on cancer metabolism and developing methods to image metabolic heterogeneity and superimpose it to the genetic heterogeneity found in tumours.

David Leslie

Full Professor of Diabetes and Autoimmunity Queen Mary University, London

r.d.g.leslie@qmul.ac.uk

Professor David Leslie is consultant physician at St Bartholomew's Hospital and Professor of Diabetes and Autoimmunity at the Blizard Institute, Queen Mary, University of London. He was recently elected President of The Association of Physicians of Great Britian and Ireland.

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He qualified and trained at Imperial College and subsequently at King's College Hospital and Royal Victoria Infirmary, Newcastle. He was an MRC Travelling Fellow at the University of Chicago, USA, and Welcome Trust Senior Clincal Research Fellow at both King's College and Charing Cross and Westminster Medical Schools. He has an interest in the cause of autoimmune diabetes through the study of twins and disease syndromes.

Research Interests

Professor Leslie has been Principle Investigator of three major EU programmes (EXALT, BLUEPRINT and Action LADA) and Founding Chairman of T1DUK. His research is based on the use of cutting-edge technology applied to unique cohorts (e.g. twins and adult onset autoimmune diabetes patients) to define the nature and origins of type 1 diabetes. These results led to work as Principle Investigator of three major EU programmes (EXALT, BLUEPRINT and Action LADA). He has been awarded lectures on several continents, e.g. Royal College of Physicians (London) Lecture, The Lily Lecture (Ireland), Niall O’Mara Lecture (Ireland), Silver Jubilee Oration (India), Xiangya Lecture (China). He held Visiting Chairs in USA (Chicago and Kansas) and Europe (Rome) and is an Emeritus Professor in China (Central South University). He was Senior Examiner Chinese University Hong Kong in 2013 and am currently am the founding Chairman of T1DUK, a UK consortium of leading UK researchers set up to investigate and prevent type 1 diabetes. Notable awards include: a Medical Research Council Travelling Fellowship to USA, the Royal College of London Leonard Simpson Fellowship and Wellcome Trust Senior Fellowship in Clinical Science. He was co-author of an award-winning textbook (BMA Book of the Year Award 2009), Director of the Mendel Institute, Rome, Italy, Co-Editor of Diabetes Metab. Res. Rev., Reviews Editor of Diabetic Medicine and served on the Editorial Board of Diabetes Care.

Alessandro Loppini

Assistant Professor in Applied Physics at Università Campus Bio-Medico di Roma

a.loppini@unicampus.it

Alessandro Loppini, PhD in Biomedical Engineering (2016) at University Campus Bio-Medico of Rome. Postdoctoral Fellow at University Campus Bio-Medico of Rome (2017-2018). Assistant Professor of Applied Physics since November 2018 at University Campus Bio-Medico of Rome.

 

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Alessandro Loppini graduated in Biomedical Engineering at “Università Campus Bio-Medico di Roma” in 2011 with the highest grades. In 2016, he obtained his PhD in Biomedical Engineering at “Università Campus Bio-Medico di Roma”. His PhD research focused on mathematical modelling of excitable biological tissues, with particular regards to beta-cells electrophysiology. As a PhD student, he spent visiting periods in the Department of Information Engineering at “Università degli studi di Padova” and in the Center of Polymer Studies at the “Boston University”. From 2016 to 2018, he was granted with a postdoctoral fellowship at the Department of Engineering of “Università Campus Bio-Medico di Roma”. Since 2018, he is Assistant Professor of Applied Physics at University Campus Bio-Medico of Rome.

Research interest

His research activity focuses on the mathematical modelling of biological processes and cells physiopathology, with particular regards to excitable cells and media, such as pancreatic β-cells, neurons and heart tissue. In this context, main research objectives are related to the identification of key molecular mechanisms at the basis of insulin release, information flow within neuronal networks and of arrhythmias and fibrillation development in heart. He is also interested in complex network theory and its application to biological systems, numerical computing applied to the resolution of ODE and PDE systems, parallel computing, and statistical analyses applied to biological and medical data.

Mauro Maccarrone

Full Professor of Biochemistry, Università Campus Bio-Medico di Roma

m.maccarrone@unicampus.it

Mauro Maccarrone, Dr. Enzymology and Bio-Organic Chemistry, is Professor and Chair of Biochemistry and Molecular Biology, and Coordinator of the Bachelor’s Degree in Food Science and Human Nutrition at the School of Medicine, Campus Bio-Medico University of Rome. 

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He is the Director of the Laboratory of Lipid Neurochemistry at the European Center for Brain Research (CERC)/IRCCS Santa Lucia Foundation, Rome, Italy. He has been awarded the “4th Royan International Research Award for Reproductive Biomedicine”, the “2007 IACM Award for Basic Research” and the “2016 Mechoulam Award”, and has been Chair of the 2015 Gordon Research Conference on “Cannabinoid Function in the CNS”. He serves as referee for several journals of science (including Science, Nature Medicine, JAMA, PNAS, Blood) and for several scientific associations (including German Research Foundation (DFG), The Wellcome Trust, the Medical Research Council (MRC), the Gordon Research Conferences (GRC)), and the NASA Postdoctoral Program (NPP). In the field of lipid signaling, he published > 485 full papers, of which 55 with I.F. ≥ 9 and 45 with ≥ 100 citations (total I.F. > 2410; citations >15180, h-index = 64 according to Scopus).
         

Research Interests

His research activity is focused in understanding the pathophysiological role of several families of bioactive lipids (endocannabinoids and specialized pro-resolving lipid mediators).

Salvatore Mangione

Associate Professor of Medicine and Director Humanities Track, History of Medicine, and Medical Cineforum programs, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania (USA)

salmangione@gmail.com

Salvatore Mangione, MD, is a clinician-educator with a long interest in physical diagnosis, medical history, community service and the role of the humanities in medicine. His innovative programs and engaging teaching style have been recognized by multiple teaching awards, and his work has been featured in the New York Times, the Los Angeles Times, the Wall Street Journal, the BBC, CNN, NPR, and Forbes. Dr. Mangione has been an invited speaker at many national and international meetings, especially in regard to using visual arts to teach bedside observation. He is the author of the book Secrets in Physical Diagnosis.

 

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Dr. Sal Mangione is a clinician-educator with a long interest in Physical Diagnosis, Medical History and community service. After obtaining his MD summa cum laude from the Catholic University of Rome, Dr. Mangione trained in Internal Medicine and Pulmonary and Critical Care Medicine at the Medical College of Pennsylvania, before eventually moving to Jefferson Medical College where he is currently Associate Professor of Medicine, Associate Program Director for the Internal Medicine Residency, Director of the second year Physical Diagnosis Course, and coordinator for the History of Medicine lecture series and the Jefferson Medical Cineforum. Dr. Mangione’s innovative programs and engaging teaching style have been recognized by multiple awards for excellence in clinical teaching, including the 2005 Golden Apple Award, the 2006 Jefferson Portrait Presentation, and the 2009 Lindback Award. His work has also been featured in the New York Times, the Los Angeles Times, the Wall Street Journal, the BBC, CNN and NPR. (The New York Times, July 13, 1999) In the 1990s Dr. Mangione published a series of landmark articles on the decline of basic clinical skills like auscultation among primary care trainees. This launched an interest in rekindling the bedside, which eventually led to the introduction of objective assessment during both the National Board of Medical Examiners (NBME) test and also during the American Board of Internal Medicine (ABIM) certification exam. Dr. Mangione collaborated with the ABIM on several research projects related to physical diagnosis, and also served on the ABIM committee that developed a Physical Examination Module for the Internal Medicine recertification exam. He also served on the NBME committee that finalized the Clinical Skills Exam, and has contributed the physical diagnosis chapter for the 14th edition of the American College of Physicians MKSAP. Dr.Dr. Sal Mangione is a clinician-educator with a long interest in Physical Diagnosis, Medical History and community service. After obtaining his MD summa cum laude from the Catholic University of Rome, Dr. Mangione trained in Internal Medicine and Pulmonary and Critical Care Medicine at the Medical College of Pennsylvania, before eventually moving to Jefferson Medical College where he is currently Associate Professor of Medicine, Associate Program Director for the Internal Medicine Residency, Director of the second year Physical Diagnosis Course, and coordinator for the History of Medicine lecture series and the Jefferson Medical Cineforum. Dr. Mangione’s innovative programs and engaging teaching style have been recognized by multiple awards for excellence in clinical teaching, including the 2005 Golden Apple Award, the 2006 Jefferson Portrait Presentation, and the 2009 Lindback Award. His work has also been featured in the New York Times, the Los Angeles Times, the Wall Street Journal, the BBC, CNN and NPR. (The New York Times, July 13, 1999) In the 1990s Dr. Mangione published a series of landmark articles on the decline of basic clinical skills like auscultation among primary care trainees. This launched an interest in rekindling the bedside, which eventually led to the introduction of objective assessment during both the National Board of Medical Examiners (NBME) test and also during the American Board of Internal Medicine (ABIM) certification exam. Dr. Mangione collaborated with the ABIM on several research projects related to physical diagnosis, and also served on the ABIM committee that developed a Physical Examination Module for the Internal Medicine recertification exam. He also served on the NBME committee that finalized the Clinical Skills Exam, and has contributed the physical diagnosis chapter for the 14th edition of the American College of Physicians MKSAP. Dr.Mangione has lectured extensively on bedside diagnosis, both nationally and internationally, including England, Canada, South America and New Zealand. He has been an invited speaker at many national and international meetings and multitudes of medical Grand Rounds, especially in regard to the role of visual arts as a way to teach bedside observation. He’s also the author of an audio-CD on chest sounds and of the book Secrets in Physical Diagnosis, which has now entered its 2nd edition, has been translated in six languages, and was hailed as “one of the more ‘fun’ books to read” by Doody Review Services. In addition to his interests in clinical skills and medical history, Dr. Mangione has also been actively involved in asthma education, creating (and directing for six years) a unique and innovative vehicle: The AsthmaBUS? -- a red, double-decker Bus that he bought in London in 1999, shipped to Philadelphia, and eventually outfitted so to provide asthma education and screening for 15,000 Philadelphia middle-school children. For this he received a community service award from the City of Philadelphia, the 2001 American Institute of Architects Award for most innovative exhibit, and the 2004 Presidential Award by the American College of Chest Physicians. Dr. Mangione was also part of Dr. Hojat’s original team that developed the Jefferson Empathy Scale, and he has maintained an active interest in rekindling empathy through the humanities. To this end, he has created a Jefferson History of Medicine course and a Medical Cineforum. He’s now at work to develop a theater program, so to foster empathy by having students participating in acting and theatrical performances.

Áine McKnight

Professor of Viral Pathology at the Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London

a.mcknight@qmul.ac.uk

Professor McKnight has dedicated her career to HIV/AIDS research. Her research group is focused on novel host cell restriction factors that inhibit HIV replication.  More recently during the Covid-19 pandemic she repurposed her skills to investigate the immune responses to SARS-CoV-2 in natural infection and after vaccination. 

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Áine was educated in Dublin, Ireland. In 1987, she joined the team of Professor Robin Weiss at the Institute of Cancer Research, London, to study the role of neutralizing antibodies to HIV-1 and HIV-2 in pathogenesis. She was awarded MSc in Immunology in 1990 by King's College, London, and a PhD in 1996 by University of London. In 2000, she won an independent fellowship by The Wellcome Trust to develop a research group to focus on non-receptor determinants of HIV replication in cells at University College London. She was subsequently awarded a Medical Research Council (MRC) Senior Non-clinical Fellowship. She moved to Bart & The London Medical School in 2006 to take up a position of Professor of Viral Pathology.

Research interest

Professor McKnight has dedicated her career to HIV/AIDS research. Her current research group is focused on novel host cell restriction factors that inhibit HIV replication. More recently during the Covid-19 pandemic she repurposed her skills to investigate the immune responses to SARS-CoV-2 in natural infection and after vaccination.

Ahuva Nissim

Full Professor of Biochemical Pharmacology, William Harvey Research Institute, Queen Mary University of London

a.nissim@qmul.ac.uk

Ahuva Nissim graduated in Molecular Immunology in 1992 from the Weizmann Institute of Science in Israel and was trained as a postdoctoral fellow at the MRC Centre for Protein Engineering in Cambridge until 1995. During this period she developed phage display semi-synthetic human antibody library, the so call ‘Nissim’ library which has been used worldwide.

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In November 2000 she was appointed as a Senior Lecturer at Queen Mary University. Her studies are interdisciplinary and involve translational research at the William Harvey Research Institute and with intensive worldwide collaborations. Her studies have been mostly focused on the mechanisms that lead to the formation of disease tissue-specific pathogenic proteins and the exploitation of identified pathogenic proteins to develop platform technologies for novel disease - and tissue-specific, diagnosis and targeted treatment.

Research Interests

The main research interest focuses on development of diseased tissue specific diagnosis and targeted immunotherapy to novel neoantigens produced specifically in diseased tissue. The role of oxidants in generation of neoantigen in the diseased tissues as a results of oxidative post-translational modification is investigated. Research is focused on arthropathies and type 1 diabetes but other autoimmune condition such as periodontal diseases have been studied. Hence, a specific targeted immunotherapy for the treatment of arthropathies has been developed. Ongoing research activities include the development of novel human antibody repertoires for engineering of new treatment modalities.

Ann Schwartz

Full Professor University of California, San Francisco Department of Epidemiology & Biostatistics

aschwartz@psg.ucsf.edu

Ann V. Schwartz, PhD, MPH is Full Professor, Department of Epidemiology and Biostatistics at the University of California, San Francisco. Dr. Schwartz's research focuses on the epidemiology and etiology of fractures, osteoporosis, and falls in older adults with diabetes.

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Research Interests

She is currently the PI of ACCORD BONE, an ancillary study to the ACCORD trial in older adults with type 2 diabetes, examining the effects of intensive glycemic control and TZD use on skeletal health. She is pursuing investigations into the reasons for reduced bone strength in type 2 diabetes, including the role of marrow fat, advanced glycation endproducts, and cortical porosity. Dr. Schwartz serves as the Director of the San Francisco Coordinating Center DXA Quality Assurance Group of Medicine.

Vittoradolfo Tambone

Full Professor of Legal Medicine, Università Campus Bio-Medico di Roma

v.tambone@unicampus.it

Vittoradolfo Tambone graduated in Medicine at “La Sapienza” University of Rome, obtained a PhD in Bioethics  at “Sacred Hearth” University of Rome, and another Phd  in Moral Theology in “Holy Cross” University of Rome.

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At present he is: a) Full Professor of Legal Medicine and Bioethics, b) Coordinator of Bioethics Service of the University Hospital Campus Bio-Medico of Rome, c) Member of the Executive Committee of The Institute of Scientific and Technological Action of the University Campus Bio-Medico of Rome, d) Visiting professor at The University of Navarra (Pamplona-Spain) and at Catholic University of Buenos Aires (Buenos Aires – Argentina), e) Coordinator of the working group of the Italian Legal Medicine College on Legal Medicine, Bioethics and Robotics, f) Member of the Study Group of the Italian Society of Legal Medicine and Insurance (SIMLA) on Ethical Consultancy (GIBCE), f) Member of several Editorial Boards of international scientific journals, g) Faculty Member of the UCBM Doctoral program in Biomedical Science and Bioethics.

Research interests

He has a vast and consolidated expertise in: a) Clinical Bioethics applied in special way in end life management, best practice ethics and ethical consulting; b) Applied Ethics to Robotics and AI; c) Medical Humanities.  His research activity is focused in improving professionalism in the field of take care through a personalistic and multidimensional vision of research and assistance. From the methodological point of view he proposes “Conscious and Cooperative Reduction” and from the ethical one the “Well done work Ethic”.

He is Author of 6 books edited in 6 languages and of more than 60 peer-reviewed publications.

Giorgio Vivacqua

MD and PhD in Human Anatomy, Neurology specialist, Research Associate at the Department of Clinical Neuroscience, The University of Cambridge

giorgio83.vivacqua@gmail.com

Giorgio Vivacqua is Research Associate at the Department of Clinical Neuroscience of The University of Cambridge. PhD in Human Anatomy at the Sapienza University of Rome and Capital Medical University of Beijing, China. Specialist in Neurology. I have been Professor of Human Anatomy at the International Medical School - Sapienza University of Rome. My research and clinical activity is mainly focused on neurodegeneration and Movement Disorders.

 

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Master Degree, Medicine and Surgery - Sapienza University of Rome; PhD, Anatomy - Sapienza University of Rome and Capital Medical University, Beijing, China; from 2011 to 2013: post-Doctoral researcher at the Department of Human Anatomy, Sapienza University of Rome; Specialist in Neurology. Professor of Human Anatomy, International Medical School, Sapienza University of Rome, until 2017. From October 2017 to September 2018: Research Fellowship Award European Academy of Neurology and International Movement Disorders Society - Department of Clinical Neuroscience, The University of Cambridge; from October 2018 to date: Research Associate, Department of Clinical Neurosciences, The University of Cambridge.

Research interest

His research activity focuses on two main fields: determination of the physiological and pathogenic role of α- synuclein in Parkinson's disease and atypical parkinsonisms, with particular attention to the detection of α-synuclein in pheripheral tissues and biological fluids, in order to develop a possible biomarker for synucleinopathies. Study of the spinal cord in experimental models of parkinsonsisms, in order to understand the anatomical bases underlying clinical symptoms poorly responsive to dopaminergic therapy and probably related to the involvement of the spinal cord.

Selected Publications

-Vivacqua et al., 2019. Motor neurons pathology after chronic exposure to MPTP in mice. Neurotox Res. DOI 10.1007/s12640-019-00121-y

-Vivacqua et al., 2019. Salivary alpha-synuclein in the diagnosis of Parkinson’s disease and progressive sopranuclear palsy. Parkinsonism Relat Disord. pii: S1353-8020(19)30060-4.

-Vivacqua et al., 2016. Abnormal salivary total and oligomeric alpha-synuclein in Parkinson’s disease.

PLoS One;11(3):e0151156.

-Vivacqua et al., 2012. Loss of Spinal motor neurons and alteration of alpha-synuclein immunostaing in MPTP induced parkinsonism in mice. J Chem Neuroanat;44(2):76-85.

-Vivacqua et al., 2011. Spinal cord and parkinsonism: neuromorphological evidences in humans and experimental studies. J Chem Neuroanat;42(4):327-40.

-Vivacqua et al., 2009. Immunolocalization of alpha-synuclein in the rat spinal cord by two novel monoclonal antibodies. Neuroscience;158(4):1478-87.

Janindra Warusavitarne

Consultant Colorectal Surgeon at St Mark’s Hospital in London

Colorectal@btinternet.com

Mr Janindra Warusavitarne, is a Consultant Colorectal Surgeon at St Mark’s Hospital in London specialising in intestinal failure, inflammatory bowel disease, Anal fistula, haemorrhoids and colorectal cancer.

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He is the lead surgeon for inflammatory bowel diseases at St Mark’s Hospital, London, an honorary senior lecturer at Imperial College and conjoint senior lecturer at the University of New South Wales.

He is part of the executive team conducting the European Board qualification for colorectal surgery and a visiting scientist to the Garvan Institute of Medical Research. In addition he sits on the education committee of the European Society of  Coloproctology.

Janindra is considered a key opinion leader and innovator and has been involved in many new procedure.

Christine Watson

Full Professor of Cell and Cancer Biology, Division of Cellular and Molecular Pathology, Department of Pathology University of Cambridge

cjw53@cam.ac.uk

I graduated with an Honours degree in Biochemistry from the University of Glasgow and a PhD in Molecular Genetics from Imperial College London. Following postdoctoral work at the Institute of Cancer Research in London and the University of St Andrews, I moved to the Roslin Institute in Edinburgh where I set up my own laboratory working on mammary gland biology.

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I moved to Cambridge in 1998. I am a member of the Nuffield Council on Bioethics and Deputy Editor of Breast Cancer Research. I am a Fellow of the Higher Education Academy. In 2017 I was elected to the Fellowship of the Academy of Medical Sciences.

Research Interests

Mammary gland development and breast cancer.

Research in my laboratory is focused on understanding the molecular and genetic mechanisms that control two essential processes for mammary gland development: commitment of stem cells to the luminal and basal lineages and the execution of cell death and tissue remodelling during post-lactational regression (involution). We use insights gained from this work to develop new approaches for the detection and treatment of breast cancer.

Tracey Wilkinson

Principal Anatomist and Director of Centre for Anatomy and Human Identification, University of Dundee Associate Dean Learning and Teaching, School of Science and Engineering

a.t.wilkinson@dundee.ac.uk

Professor Wilkinson is medically qualified with a PhD in biomechanics and anatomy, and has worked in several countries, including Germany, parts of Africa and all four of the home countries in the UK (England, Wales, Northern Ireland and Scotland).

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Her main interest lies in learning and teaching, with many years of experience in higher education, mostly involving undergraduate and postgraduate medical, dental and anatomy students, but also several paramedical disciplines. She runs the Anatomical Society’s and American Association of Anatomy’s international Anatomy Training Programme for young scientists, and was on the Organising Committee for the International Federation of Associations of Anatomists conference held in London, UK in 2019.

Research interest

She has published on a variety of subjects, including medical and anatomy education, biomechanics, clinical anatomy, functional anatomy and human variation.