Daniel Sifrim
Biografia
Daniel Sifrim is a Gastroenterologist, trained in Argentina and Belgium, with both clinical and scientific interest in oesophageal benign disorders. He contributed with the development of diagnostic techniques for oesophageal motility disorders and gastro-oesophageal reflux disease (high resolution manometry, oesophageal impedance and salivary pepsin measurements). He is Emeritus Professor of Gastrointestinal Physiology at Barts and the London School of Medicine, Queen Mary University of London, UK. He is co-director of the Neurogastroentertology Department at Princess Grace Hospital, London.
Curriculum
Professional Training 1980 - 1983 Resident (registar) in Internal Medicine
Carlos Durand Hospital, Buenos Aires
1983 - 1985 Resident (registrar) in Gastroenterology
A. Posadas Hospital, Buenos Aires
1986 - 1987 Chief of Residents in Gastroenterology
A. Posadas Hospital Buenos Aires
1987 - 1988 Clinical Research Fellow
A. Posadas Hospital, Buenos Aires
Department of Medicine, Division of Nutrition.
1989 - 1990 Clinical Research Fellow
A. Posadas Hospital, Buenos Aires
Department of Medicine, Division of Gastroenterology.
Program "Gastrointestinal Motility Disorders"
1990 - 1994 Research Fellow
University Hospital Gasthuisberg, Leuven, Belgium
Department of Medicine, Division of Gastroenterology.
"Esophageal Motility Disorders"
Director: Prof. Gaston Vantrappen MD, Ph.D.
Academic Appointments 1989 - 1990 Instructor in Medicine
Buenos Aires University, School of Medicine
1989 - 1990 Scientific Advisory Council, Enteral
Nutrition.Buenos Aires University, School of Medicine
1994 - 2004 Associate Professor of Medicine
Faculty of Medicine. K.U.Leuven. Belgium
2004 - Professor of Medicine
Faculty of Medicine. K.U.Leuven. Belgium
2009 - Professor of GI Physiology
Barts and The London School of Medicine and
Dentistry, Queen Mary, University of London. U
Certification and Licensure 1980 Medical Doctor Licensure (M.D.) equivalent MB BS
Ministry of Public Health, Argentina.
1986 Board Certification in Gastroenterology
Argentine Society of Gastroenterology.
Ministry of Public Health, Argentina.
1992 Medical Doctor Certificate
Ministry of PublicHealth and Education, Spain.
1997 Medical Doctor Degree
Ministry of PublicHealth, Belgium.
2010 Board Certification in Gastroenterology
Ministry of Public Health, Spain
2009 GMC full registration UK (GMC number 7041567)
Clinical work and experience
1983-1987 Clinical Staff. Internal Medicine
Intensive Care Unit. Anchorena Hospital, Buenos Aires, Argentina
1987-1990 Clinial Staff. Gastroenterology Department
A. Posadas Hospital. Buenos Aires, Argentina. Honorary Contract.
1990 - 1994 Research Fellow
University Hospital Gasthuisberg, Leuven, Belgium
Department of Medicine, Division of Gastroenterology.
1994 - 2006 Clinical Research Esophageal Disorders
University Hospital Gasthuisberg, Leuven, Belgium
Department of Medicine, Division of Gastroenterology.
2006 - 2009 Consultant Gastroenterology.
Outpatient Clinic Neurogastroenterology
University Hospital Gasthuisberg, Leuven, Belgium
Department of Medicine, Division of Gastroenterology.
2009 - Director Upper Gastrointestinal Physiology Unit Royal London Hospital, UK (Honorary Contract)
Department Digestive Diseases. Barts and the London School of Medicine and Dentistry, Queen Mary University of London
Associate Editor “Journal of Neurogastroenterology and Motility”
Associate Editor “Journal of Clinical Gastroenterology”
Member of editorial board, “American Journal of Gastroenterology” and Current Treatment Options in Gastroenterology
Reviewer for “Gastroenterology”.
“Gut”
“European Journal of Gastroenterology and Hepatology”
“Gastroenterologie Clinique et Biologie”
“American Journal of Gastroenterology”
“American Journal of Physiology”
Prizes
1. American Gastroenterology Association, Janssen Award in Basic Science and Clinical Research, 2003.
2. Research in Neurogastroenterology Award Mme van Genechten-Paternoster- Prof. Vantrappen (Belgium) 2005
PUBBLICAZIONI
1: Sawada A, Sifrim D. How to recognize and treat rumination syndrome. Curr Opin
Gastroenterol. 2023 Jul 1;39(4):340-346. doi: 10.1097/MOG.0000000000000937. Epub
2023 Apr 25. PMID: 37097822.
2: Sawada A, Sifrim D, Fujiwara Y. Esophageal Reflux Hypersensitivity: A
Comprehensive Review. Gut Liver. 2023 Jan 2. doi: 10.5009/gnl220373. Epub ahead
of print. PMID: 36588526.
3: Sawada A, Rogers B, Visaggi P, de Bortoli N, Gyawali CP, Sifrim D. Effect of
hiatus hernia on reflux patterns and mucosal integrity in patients with non-
erosive reflux disease. Neurogastroenterol Motil. 2022 Nov;34(11):e14412. doi:
10.1111/nmo.14412. Epub 2022 May 20. PMID: 35593218.
4: Savarino E, Bhatia S, Roman S, Sifrim D, Tack J, Thompson SK, Gyawali CP.
Achalasia. Nat Rev Dis Primers. 2022 May 5;8(1):28. doi:
10.1038/s41572-022-00356-8. PMID: 35513420.
5: Fass R, Boeckxstaens GE, El-Serag H, Rosen R, Sifrim D, Vaezi MF. Gastro-
oesophageal reflux disease. Nat Rev Dis Primers. 2021 Jul 29;7(1):55. doi:
10.1038/s41572-021-00287-w. PMID: 34326345.
6: Gyawali CP, Tutuian R, Zerbib F, Rogers BD, Frazzoni M, Roman S, Savarino E,
de Bortoli N, Vela MF, Sifrim D. Value of pH Impedance Monitoring While on
Twice-Daily Proton Pump Inhibitor Therapy to Identify Need for Escalation of
Reflux Management. Gastroenterology. 2021 Nov;161(5):1412-1422. doi:
10.1053/j.gastro.2021.07.004. Epub 2021 Jul 14. PMID: 34270955.
7: Sawada A, Lei WY, Zhang M, Lee C, Ustaoglu A, Chen CL, Sifrim D. Esophageal
mucosal sensory nerves and potential mechanoreceptors in patients with
ineffective esophageal motility. Neurogastroenterol Motil. 2022
Feb;34(2):e14205. doi: 10.1111/nmo.14205. Epub 2021 Jun 21. PMID: 34152070.
8: Ustaoglu A, Nguyen A, Spechler S, Sifrim D, Souza R, Woodland P. Mucosal
pathogenesis in gastro-esophageal reflux disease. Neurogastroenterol Motil. 2020
Dec;32(12):e14022. doi: 10.1111/nmo.14022. Epub 2020 Oct 28. PMID: 33118247.
9: Sifrim D, Roman S, Savarino E, Bor S, Bredenoord AJ, Castell D, Cicala M, de
Bortoli N, Frazzoni M, Gonlachanvit S, Iwakiri K, Kawamura O, Krarup A, Lee YY,
Soon Ngiu C, Ndebia E, Patcharatraku T, Pauwels A, Pérez de la Serna J, Ramos R,
Remes-Troche JM, Ribolsi M, Sammon A, Simren M, Tack J, Tutuian R, Valdovinos M,
Xiao Y, Zerbib F, Gyawali CP. Normal values and regional differences in
oesophageal impedance-pH metrics: a consensus analysis of impedance-pH studies
from around the world. Gut. 2020 Oct 9:gutjnl-2020-322627. doi:
10.1136/gutjnl-2020-322627. Epub ahead of print. PMID: 33037054.
