Anna Rita Franco Migliaccio

I have more than 40 years of experience in research in Experimental Hematology. My training involved three distinctive post-doctoral fellowships with Prof. C. Peschle (Italy), Prof. G. Wagemaker (The Netherlands), Prof. JWA Adamson (USA). I have then co-directed with Prof. Adamson the laboratory of Hematopoietic Growth Factors at the NYBC (New York, NY, USA) for almost 9 years. Here I was responsible for developing GMP procedures to assess the quality of cord blood being stored for transplantation. I established my first independent laboratory in 1998 at the Istituto Superiore di Sanita’, Rome Italy. One of my scientific accomplishments as independent investigator was to identify that mice carrying the hypomorphic Gata1low mutation develops myelofibrosis. This discovery led to my inclusion in the first submission of the PPG on MPN-RC by Ron Hoffman in 2003, funded by the NCI in 2006.

Academic appointments

01/06/2021-present Professor of Histology and Embryology Università Campus Bio-Medico di Roma, Italy

01/06/2021-present Senior Investigator Altius Institute for Biomedical Sciences Seattle, USA

11/03/2014-31/05/2021 Full Professor “Chiara Fama” Histology and Embryology Faculty of Medicine University of Bologna, Italy

Member of Editorial Boards and Study Sections

2022 Editor with Ronald Hoffman of a special issue of International Journal of Molecular Sciences (ISSN 1422 0067), that belong to the section "Molecular Pathology, Diagnostics, and Therapeutics".

2022 Editor Special topic of Frontiers in Hematology, Red Cells, Iron and Erythropoiesis

2022 Section Head for Hematopoiesis Faculty Opinion

2022-2024 NIH, Member for ZRG1 VH-B, “Basic Biology of Blood, Heart and Vasculature” and “Hemostasis, Thrombosis, Blood Cells and Transfusion Medicine”

2021 NIH, ad hoc Member for ZRG1 VH-B, “Basic Biology of Blood, Heart and Vasculature” and “Hemostasis, Thrombosis, Blood Cells and Transfusion Medicine”

2019-2022 Vice Chair, review panel Marie-Curie individual Fellowships

Education

1972-1975 PhD in Natural Science (110/110 cum laude) University of Naples, Naples, Italy

1975-1977 PhD in Biological Science (110/110 cum laude) University of Naples, Naples, Italy

H-index = 40 (calculated by Scopus); 7117 total citations

https://www.scopus.com/authid/detail.uri?authorId=7005863261

https://www.webofscience.com/wos/author/record/GWZ-9323-2022

The list of pubblications only of the 2022:

1. Verachi P, Gobbo F, Martelli F, Martinelli A, Sarli G, Dunbar A, Levine RL, Hoffman R, Massucci M T, Brandolini L, Giorgio C, Allegretti M, Migliaccio AR. The CXCR1/CXCR2 Inhibitor Reparixin Alters the Development of Myelofibrosis in the Gata1low Mice. Frontiers in oncology (2022) 12, 853484. https://doi.org/10.3389/fonc.2022.853484

2. Varricchio L, Geer E B, Martelli F, Mazzarini M, Funnell A, Bieker J, Papayannopoulou T, Migliaccio AR, Hypercortisolemic Cushing's patients possess a distinct class of hematopoietic progenitor cells leading to erythrocytosis. Haematologica (2022) doi:10.3324/haematol.2021.280542

3. Verachi P, Gobbo F, Martelli F, Falchi M, di Virgilio A, Sarli G, Wilke C, Bruederle A, Prahallad A, Arciprete F, Zingariello M, Migliaccio AR. Preclinical studies on the use of a P-selectin-blocking monoclonal antibody to halt progression of myelofibrosis in the Gata1low mouse model. Exp Hematol (2022) S0301-472X(22)00698-1. doi: 10.1016/j.exphem.2022.09.004

4. Melo-Cardenas J, Bezavada L, Chase Crawford J, Gurbuxani S, Cotton A, Kang G, Gosset J, Marinaccio C, Weinberg R, Hoffman R, Migliaccio AR, Zheng Y, Derecka M, Rinaldi R C, Crispino J, IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasm, Blood 2022 [in press]

5. Migliaccio AR, Balduini A, Zhan H, Megakaryocytes as Regulators of Tumor Microenvironments (Editorial), Frontiers in Oncology, 2022 [in press]

Complete List of Published Work: https://www.ncbi.nlm.nih.gov/myncbi/anna%20rita.migliaccio.1/bibliography/public/?sortby=pubDate&sdirection=descending