Lazzaro Di Biase
Biografia
Dr Lazzaro di Biase is a Clinical Neurologist with a PhD in Science of Aging and Tissue Regeneration at the Campus Bio-Medico University (UCBM) of Rome. He is the Scientific Director of the Brain Innovations Lab, an a UCBM spinoff. He has clinical and international research experience in the field of neurodegenerative disease and movement disorders. Dr di Biase worked as a clinical researcher in the Nuffield Department of Clinical Neurosciences at Oxford University and University College London, UK and as a visiting doctor in the Movement Disorders Clinic at the Toronto Western Hospital, Canada. His expertise and innovative research in clinical neurology and neurophysiology and developing new technologies has led to advances in the differential diagnosis of tremor syndromes, the diagnosis of Parkinson's Syndrome, monitoring and adaptive closed-loop therapy, with four patents filed as inventor and an innovative startup founded. On an academic level, dr. Di Biase is a tutor in the teaching of Human Physiology S.S.D. BIO/09, and of Neurology and Psychiatry S.S.D. MED/26; in addition, since 2021 he has been a contract professor for the teaching activity of Phisiology S.S.D. BIO/09, for the Medicine and Surgery English degree course, in the departmental faculty of Medicine and Surgery of the Campus Bio-Medico University of Rome.
Curriculum
Education
2010 Degree in Medicine and Surgery - University Campus Bio-Medico of Rome, Italy - degree mark 110/110 cum laude.
2016 Neurology specialization - University Campus Bio-Medico of Rome, Italy - degree mark 50/50 cum laude.
2020 PhD – Integrated Biomedical Science and Bioethics - Science of Aging and Tissue regeneration. University Campus Bio-Medico of Rome, Italy.
Professional Experience
2011 - 2016 Neurology Residency Training Program - University Campus Bio-Medico of Rome, Italy.
2011 - 2016 Training in Movement disorders. University Campus Bio-Medico of Rome, Italy.
2011 - 2016 Training in botulinum toxin therapy in Neurology
2014 - 2016 Training in neuropsychological assessment. University Campus Bio-Medico of Rome, Italy.
2015 Visiting doctor. University of Toronto. Movement Disorders Clinic, Toronto Western Hospital. Training in Movement Disorders and Deep Brain Stimulation therapy.
2016 - 2018 Clinical research fellow, University of Oxford, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK
2016 Clinical research fellow, Medical Research Council Brain Network Dynamics Unit, Oxford, UK
2016 Clinical research fellow, Sobell Department of Motor Neuroscience and Movement Disorders, Unit of Functional Neurosurgery, University College London, London, UK
2017 - present Neurologist, Department of Neurology, Campus Bio-Medico University of Rome
2017 - present Movement disorders and Parkinson’s disease clinic, Department of Neurology, Campus Bio-Medico University of Rome
Teaching Experience
2006 - 2020 Tutoring for teaching and research activities for the course of Physiology. Faculty of Medicine and Surgery; at the University Campus Bio-Medico of Rome, Italy.
2018 - present Tutoring for the Neurology residency training program. Faculty of Medicine and Surgery; at the University Campus Bio-Medico of Rome, Italy.
2014 - 2020 Assignment for tutoring activities in the teaching of Human Physiology S.S.D. BIO / 09, for the Master's Degree Course in Medicine and Surgery, Campus Bio-Medico University of Rome.
2018 - present Assignment of coordinated and continuous autonomous collaboration for the teaching assistance activities, in the context of the teaching of Neurology and Psychiatry S.S.D. MED / 26, for the Master's Degree Course in Medicine and Surgery, at the Campus Bio-Medico University of Rome.
2021 - present Assignment of coordinated and continuous autonomous collaboration for the teaching activities, at the Campus Bio-Medico University of Rome, as a contract lecturer for the teaching activity of Phisiology S.S.D. BIO / 09, for the Medicine and Surgery English degree course, in the departmental faculty of Medicine and Surgery.
2021 Lecture: Luiss University - Law, Digital Innovation and Sustainability English Master's degree program - Brain Innovations Healthcare 4.0
2022 Master in Artificial Intelligence and Telemedicine – University of Parma
- Lecture: Wearable for Telemedicine
- Lecture: Telemedicine in chronic diseases – The Neurologic patient.
Scientific articles Reviewer Activities
Neurology Section Editor for Annals of Medicine
Editorial topic board member of Sensors
Editorial board member of International Journal of Neuroscience
PUBBLICAZIONI
di Biase L, Di Santo A, Caminiti ML, Pecoraro PM, Di Lazzaro V. Classification of Dystonia. Life. 2022; 12(2):206. https://doi.org/10.3390/life12020206
di Biase L, Tinkhauser G, Martin Moraud E, Caminiti ML, Pecoraro PM, Di Lazzaro V. Adaptive, personalized closed-loop therapy for Parkinson's disease: biochemical, neurophysiological, and wearable sensing systems. Expert Rev Neurother. 2021 Dec;21(12):1371-1388. doi: 10.1080/14737175.2021.2000392. Epub 2021 Nov 17. PMID: 34736368.
di Biase L, Falato E, Caminiti ML, Pecoraro PM, Narducci F, Di Lazzaro V. Focused Ultrasound (FUS) for Chronic Pain Management: Approved and Potential Applications. Neurol Res Int. 2021 Jun 29;2021:8438498. doi: 10.1155/2021/8438498. PMID: 34258062; PMCID: PMC8261174.
di Biase, L., Di Santo, A., Caminiti, M. L., De Liso, A., Shah, S. A., Ricci, L., & Di Lazzaro, V. (2020). Gait analysis in Parkinson’s disease: an overview of the most accurate markers for diagnosis and symptoms monitoring. Sensors, 20(12), 3529.
Raiano, L., Di Pino, G., Di Biase, L., Tombini, M., Tagliamonte, N. L., & Formica, D. (2020). PDMeter: A Wrist Wearable Device for an at-home Assessment of the Parkinson's Disease Rigidity. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 10.1109/TNSRE.2020.2987020.
di Biase, L.; Falato, E.; Di Lazzaro, V.; ,Transcranial focused ultrasound (tFUS) and transcranial unfocused ultrasound (tUS) neuromodulation: from theoretical principles to stimulation practices.,Frontiers in Neurology,10,,549,2019
Marano, M., Naranian, T., di Biase, L., Di Santo, A., Poon, Y. Y., Arca, R., Cossu, G., Marano, P., Di Lazzaro, V., & Fasano, A. (2019). Complex dyskinesias in Parkinson patients on levodopa/carbidopa intestinal gel. Parkinsonism & related disorders, 69, 140–146.
Marano M, Lanzone J, di Biase L, Pepe A, Di Santo A, Di Lazzaro V. A rare cause of axial worsening in Parkinson's disease: A case of myasthenic pseudo-parkinsonism. Clin Neurol Neurosurg. 2019 Feb 11;179:1-3. doi: 10.1016/j.clineuro.2019.02.009. [Epub ahead of print] PubMed PMID: 30772769.
Kern DS, Picillo M, Thompson JA, Sammartino F, di Biase L, Munhoz RP, Fasano A. Interleaving Stimulation in Parkinson's Disease, Tremor, and Dystonia. Stereotact Funct Neurosurg. 2018;96(6):379-391. doi: 10.1159/000494983. Epub 2019 Jan 17. PubMed PMID: 30654368.
Marano M, Pizzicannella M, di Biase L, Rea R, Di Santo A, Martino M, Andrisani G, Pandolfi M, Di Matteo FM, Di Lazzaro V. Jejunal pulling syndrome: A peculiar LCIG complication. Parkinsonism Relat Disord. 2018 Mar 22. pii: S1353-8020(18)30131-7. doi: 10.1016/j.parkreldis.2018.03.016. [Epub ahead of print] PubMed PMID: 29588146.
di Biase L, Summa S, Tosi J, Taffoni F, Marano M, Cascio Rizzo A, Vecchio F, Formica D, Di Lazzaro V, Di Pino G, Tombini M. Quantitative Analysis of Bradykinesia and Rigidity in Parkinson's Disease. Front Neurol. 2018 Mar 6;9:121. doi: 10.3389/fneur.2018.00121. eCollection 2018. PubMed PMID: 29568281; PubMed Central PMCID: PMC5853013.
Sandoe C, Krishna V, Basha D, Sammartino F, Tatsch J, Picillo M, di Biase L, Poon YY, Hamani C, Reddy D, Munhoz RP, Lozano AM, Hutchison WD, Fasano A. Predictors of deep brain stimulation outcome in tremor patients. Brain Stimul. 2018 May - Jun;11(3):592-599. doi: 10.1016/j.brs.2017.12.014. Epub 2018 Jan 2. PubMed PMID: 29330020.
Tinkhauser G, Pogosyan A, Debove I, Nowacki A, Shah SA, Seidel K, Tan H, Brittain JS, Petermann K, di Biase L, Oertel M, Pollo C, Brown P, Schuepbach M. Directional local field potentials: A tool to optimize deep brain stimulation. Mov Disord. 2018 Jan;33(1):159-164. doi: 10.1002/mds.27215. Epub 2017 Nov 18. PubMed PMID: 29150884; PubMed Central PMCID: PMC5768242.
