Alessandro Loppini

DATA DI NASCITA: 9 Dicembre 1985

LUOGO DI NASCITA: Roma

ISTRUZIONE E FORMAZIONE

2016 Ph.D. in Ingegneria Biomedica. UCBM.

2011 Laurea Magistrale in Ingegneria Biomedica. 110/110 con lode. UCBM.

2017 5th HBP School - Future Medicine. Obergurgl, Austria. Novembre 2017. Human Brain Project Education Progamme.

2017 First International Summer Institute on Network Physiology. Como, Italia. Luglio 2017. Lake Como School of Advanced Studies.

2016 XLI Summer School on Mathematical Physics. Ravello, Italia. Settembre 2016. Istituto Nazionale di Alta Matematica, Gruppo Nazionale per la Fisica Matematica (INdAM-GNFM).

2016 XXXIX Summer School on Mathematical Physics. Ravello, Italia. Settembre 2014. Istituto Nazionale di Alta Matematica, Gruppo Nazionale per la Fisica Matematica (INdAM-GNFM).

2013 Applied Bayesian Statistics School. Como, Italia. Giugno 2013. Consiglio Nazionale delle Ricerche, Istituto di Matematica Applicata e Tecnologie Informatiche (CNR IMATI).

2012 Introduction to parallel computing: MPI and OpenMP. Roma, Italia. Giugno 2012. Consorzio Interuniversitario per le Applicazioni di Supercalcolo per Università e Ricerca (CASPUR).

CARRIERA PROFESSIONALE

2023-presente Ricercatore RTD-B in Fisica Applicata (PHYS-06/A), UCBM.

2018-2023 Ricercatore RTD-A in Fisica Applicata (PHYS-06/A), UCBM.

2021-2023 Ricercatore affiliato presso Center for Life Nano- & Neuro-Science, Istituto Italiano di Tecnologia (IIT).

2016-2018 Ricercatore Postdoc, UCBM.

Incarichi di insegnamento:

2022-presente Docente di General Physics, Biomedical Engineering and Master's Degree Program in Medicine & Surgery MedTech, UCBM.

2019-presente Docente di Physics, Master's Degree Program in Medicine & Surgery, UCBM.

2018-presente Docente di Fisica Applicata, corso di Laurea in Fisioterapia, UCBM.

2023-2026 Docente di Physiological Models, Master's Degree Program in Medicine & Surgery MedTech, UCBM.

2024-2026 Docente di Fisica Applicata, corso di Laurea in Odontoiatra e Protesi Dentaria, UCBM.

PROGETTI SCIENTIFICI (SELEZIONATI)

2022-in corso EBRAINS-Italy, CUP B51E22000150006, Finanziamento € 22370240. Ruolo: partecipante unità URT-DSFTM@UCBM.

2022-in corso EC HORIZON-RIA, MUQUABIS, Finanziamento € 6700000. Ruolo: partecipante unità UCBM.

2023-2026 PRIN 20225HYM8N, QUASAR, Finanziamento € 23501000. Ruolo: PI unità UCBM.

REVIEWER E RUOLI EDITORIALI

-Associate Editor per Frontiers in Physics (editorial board).

-Academic Editor per PLOS One (editorial board).

CONFERENZE (SELEZIONATE)

-Dynamics Days Europe 2025, Thessaloniki, Greece. “Complex Dynamics in Cardiac Systems”. Speaker and minisymposium organizer.

-Dynamics Days Europe 2024, Bremen, Germany. “Modeling, analysis, and control of cardiac dynamics”.Speaker and minisymposium organizer.

-Dynamics Days Europe 2023, Naples, Italy. “Analysis and control of cardiac dynamics: experiments, modeling, and simulations”. Minisymposium organizer.

-Metrology for Industry 4.0 & IOT 2022. “The Frontiers of Sensing: Quantum & Biosensors”. Special Session organizer.

-DPG Meeting of the Condensed Matter Section (SKM) 2021. “Spatiotemporal correlation of cardiac tissue and its variation in response to temperature”.

-Dynamics Days Europe 2021, Nice, France. “Neuronal dynamics: from single cell up to large-scale networks”. Speaker and minisymposium organizer.

-65th Biophysical Society Annual Meeting, BPS 2021. “Thermo-electric coupling in cardiac dynamics”.

-Modelling the Cardiac Function: Theory, Numerical Methods, Clinical Applications, MCF2020, Poitecnico di Milano, Milan, Italy. “Thermal Effects and Correlation Analysis on Cardiac Tissue”.

-11th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2020, Pisa, Italy. “Temperature effects and correlation analysis in cardiac tissue”.

-PLACE 2019 - Platform of Laboratories for Advances in Cardiac Experience. Centro Congressi di Confindustria, Auditorium della Tecnica, Roma, Italia. 2019. “Experiment, modeling and simulation in cardiac physiopathology”. Symposium organizer.

-XXIV Congresso Nazionale SIBPA. Università Politecnica delle Marche, Ancona, Italia. 2018. “Emergent activity of electrically-coupled β-cells: a mathematical modelling approach”.

-9th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2016, Lancaster, UK. “Role of temperature and tissue size on nonlinear cardiac dynamics”.

MEMBERSHIPS

-Istituto Nazionale di Alta Matematica, Gruppo Nazionale per la Fisica Matematica (INdAM-GNFM).

-Società Italiana di Biofisica Pura e Applicata (SIBPA).

PUBBLICAZIONI RECENTI (SELEZIONATE)

1) Angiolelli, M., Scarpetta, S., Sorrentino, P., Troisi Lopez, E., Quarantelli, M., Granata, C., Sorrentino, G., Palmieri, V., Messuti, G., Stefano, M., Filippi, S., Cherubini, C., Loppini, A., & Chiodo, L. (2025). Role of criticality in the structure-function relationship in the human brain. Physical Review Research, 7(4), 043153.

2) Crispino, A., Nicoletti, M., Loppini, A., Gizzi, A., Chiodo, L., Cherubini, C., & Filippi, S. (2025). Magnetic signature of thermoelectric cardiac dynamics. Physical Review E, 111(1), L012401.

3) Nicoletti, M., Chiodo, L., Loppini, A., Liu, Q., Folli, V., Ruocco, G., & Filippi, S. (2024). Biophysical modeling of the whole-cell dynamics of C. elegans motor and interneurons families. Plos one, 19(3), e0298105.

4)Luchetti, N., Smith, K. M., Matarrese, M. A., Loppini, A., Filippi, S., & Chiodo, L. (2024). A statistical mechanics investigation of unfolded protein response across organisms. Scientific Reports, 14(1), 27658.

5) Luchetti, N., Loppini, A., Matarrese, M. A., Chiodo, L., & Filippi, S. (2023). Structural controllability to unveil hidden regulation mechanisms in Unfolded Protein Response: The role of network models. Physica A: Statistical Mechanics and its Applications, 617, 128671.

6) Luchetti, N., Filippi, S., & Loppini, A. (2023). Multilevel synchronization of human β-cells networks. Frontiers in Network Physiology, 3.

7) Matarrese, M. A., Loppini, A., Nicoletti, M., Filippi, S., & Chiodo, L. (2022). Assessment of tools for RNA secondary structure prediction and extraction: a final-user perspective. Journal of Biomolecular Structure and Dynamics, 1-20.

8) Barone, A., Grieco, D., Gizzi, A., Molinari, L., Zaltieri, M., Massaroni, C., Loppini, A., Schena, E., Bressi, E., de Ruvo, E., Caló, L., & Filippi, S. (2022). A Simulation Study of the Effects of His Bundle Pacing in Left Bundle Branch Block. Medical Engineering & Physics, 107, 103847.

9) Loppini, A., Erhardt, J., Fenton, F. H., Filippi, S., Hörning, M., & Gizzi, A. (2022). Optical Ultrastructure of Large Mammalian Hearts recovers Discordant Alternans by in-silco Data Assimilation. Frontiers in Network Physiology, 17.

10) Scialla, S., Loppini, A., Patriarca, M., Heinsalu, E. Hubs, diversity, and synchronization in FitzHugh-Nagumo oscillator networks: Resonance effects and biophysical implications (2021) Physical Review E, 103 (5), art. no. 052211.

11) Loppini, A., Barone, A., Gizzi, A., Cherubini, C., Fenton, F.H., Filippi, S. Thermal effects on cardiac alternans onset and development: A spatiotemporal correlation analysis (2021) Physical Review E, 103 (4), art. no. L040201.

12) Stefano, M., Cordella, F., Loppini, A., Filippi, S., Zollo, L. A Multiscale Approach to Axon and Nerve Stimulation Modeling: A Review (2021) IEEE Transactions on Neural Systems and Rehabilitation Engineering, 29, art. no. 9335942, pp. 397-407.

13) Ruiz-Baier, R., Gizzi, A., Loppini, A., Cherubini, C., Filippi, S. Modelling thermo-electro-mechanical effects in orthotropic cardiac tissue (2020) Communications in Computational Physics, 27 (1), pp. 87-115.

14) Loppini, A., Gizzi, A., Cherubini, C., Cherry, E.M., Fenton, F.H., Filippi, S. Spatiotemporal correlation uncovers characteristic lengths in cardiac tissue (2019) Physical Review E, 100 (2), art. no. 020201.

15) Nicoletti, M., Loppini, A., Chiodo, L., Folli, V., Ruocco, G., Filippi, S. Biophysical modeling of C. Elegans neurons: Single ion currents and whole-cell dynamics of AWCon and RMD (2019) PLoS ONE, 14 (7), art. no. e0218738.

16) Loppini, A., Filippi, S., Stanley, H.E. Critical transitions in heterogeneous networks: Loss of low-degree nodes as an early warning signal (2019) Physical Review E, 99 (4), art. no. 040301.