Prof. Vincenzo Di Lazzaro
Biography
Actual position
Dean of the Departmental Faculty of Medicine and Surgery Campus Bio Medico University
Full Professor of Neurology Campus Bio-Medico University
Director of the School of Specialization in Neurology
Director of the Neurology Complex Operating Unit at the Campus Biomedico University Hospital of Rome
Positions held in the past
President of the Italian Society of Clinical Neurophysiology 2018-2021
1/4/2010-30/4/2012 Head of the Simple Stroke Unit Structure pertaining to the Department of Neurosciences, Catholic University, Faculty of Medicine, Rome
31/8/2008-30/4/2012 Confirmed Associate Professor Sector MED 26 Neurology at the Institute of Neurology, Catholic University, Faculty of Medicine and Surgery. Level II Medical Director Level II Neurovascular Therapy Unit
1/4/2006-30/8/2008 Unconfirmed associate professor Sector MED 26 Neurology at the Institute of Neurology Catholic University Faculty of Medicine and Surgery. II level medical director of the II level Neurovascular Therapy Unit
1/10/2004-31/3/2006 Unconfirmed associate professor Sector MED 26 Neurology at the Institute of Neurology Catholic University Faculty of Medicine and Surgery. II level medical director.
1/3/1997-30/9/2004 University researcher at the Institute of Neurology Catholic University Faculty of Medicine and Surgery Catholic University, Faculty of Medicine Rome.
1/7/1990 - 28/2/1997 "University Internal Doctor with Assistance Tasks" at the Neurology Division pertaining to the Institute of Neurology of the Catholic University, Faculty of Medicine Rome
Curriculum
Scientific activity
The research activity has been carried out continuously since 1990, embracing various fields of neuroscience and has led to an important advance in knowledge in the following sectors: diagnosis of neurological diseases with particular reference to dementias and myelopathies; evaluation of the effect of drugs and/or surgical therapies in various neurological pathologies; non-invasive study of the physiology of the normal and pathological human cerebral cortex and study of cerebral plasticity in humans; study of the pathophysiology of Parkinson's disease through direct recording of basal ganglia activity; development of invasive and non-invasive neuromodulation methods, with therapeutic potential in various neurological pathologies, in particular cerebral stroke, Parkinson's disease and motor neuron diseases. The scientific activity was also carried out in collaboration with prestigious international centers (in particular: "Sobell Department of Motor Neuroscience and Movement Disorders Institute of Neurology London UK"; "Department of Clinical Neurology University of Oxford UK"; "Department of Neurology, Johann Wolfgang Goethe-University, Frankfurt, Germany”; Department of Physical Medicine & Rehabilitation, Spaulding Rehabilitation Hospital & Massachusetts General Hospital, Harvard Medical School).
The scientific production (over 450 publications in journals with impact factor) has received wide recognition from the scientific community as evidenced by the high number of citations in the international literature (>38.000) and by the H-Index: 84
Collaboration in Scientific Journals
Editor of Case Reports in Medicine
Editor of Neurology Research International
Member of the Editorial Board of Clinical Neurophysiology (Official Body of the International Federation of Clinical Neurophysiology)
Member of the Editorial Board of Brain Stimulation
Prizes and Awards
Corresponding Member of the German Society for Clinical Neurophysiology and Functional Neuroimaging 2018-2021
Ellermann Lecture (Ellermann Foundation of the Medical Faculty of Bern). University of Bern Switzerland (2005)
Winner of the Sapio Award for Italian Research 2005 edition
Clinical activity and management experience.
The assistance activity was carried out from 1990 to 30 April 2012 at the Neurological Clinic of the Policlinico A. Gemelli, from 1 May 2012 he assumed the Directorate of the Chair of Neurology and of the School of Specialization in Neurology Faculty of Medicine and Surgery of the University Biomedical campus.
The areas of greatest clinical interest are represented by: 1) cerebrovascular diseases; 2) myeloradiculopathies; 3) neurodegenerative pathologies (in particular dementias and motor neuron diseases); 4) movement disorders and cerebellar syndromes; 5) neuromuscular diseases.
In 2005 he started the Neurovascular Therapy Unit (Stroke Unit) of the “A. Gemelli” in Rome and until 30 April 2012 he held the position of head of the Unit recognized as a II level UTN by the Lazio Region (DGR 420/07).
From 2007 to April 2012 he held the position of Director of the research center for Parkinson's disease at the Catholic University. You have more than twenty years of teaching experience at all levels of university and post-graduate training. Professor of Neurology from 2004 to 2012 in the Degree Course in Medicine, in Three-year Degree Courses and in all the Specialization Schools of the Medical Area of the Faculty of Medicine and Surgery of the Catholic University. From 2003 to 2012 you held the role of coordinator of the teaching activity for Neurology for the Faculty of Medicine of the Catholic University.
PUBLICATIONS
Selection of publications
Doubtful R, Pellegrino G, Ranieri F, Di Pino G, Capone F, Dileone M, Iodice R, Ruggiero L, Tozza S, Uncini A, Manganelli F, Di Lazzaro V. BDNF polymorphism and interhemispheric balance of motor cortex excitability: a preliminary study. J Neurophysiol 2022
Di Lazzaro V, et al. Diagnostic contribution and therapeutic perspectives of transcranial magnetic stimulation in dementia. Clin Neurophysiol. 2021
Guerra A, Ranieri F, Falato E, Musumeci G, Di Santo A, Asci F, Di Pino G, Suppa A, Berardelli A, Di Lazzaro V. Detecting cortical circuits resonant to high-frequency oscillations in the human primary motor cortex: a TMS-tACS study. Ski Rep. 2020
Ranieri F, Coppola G, Musumeci G, Capone F, Di Pino G, Parisi V, Di Lazzaro V. Evidence for associative plasticity in the human visual cortex. Brain Stimul. 2019
Di Lazzaro V et al. Noninvasive Stimulation of the Human Brain: Activation of Multiple Cortical Circuits. Neuroscientist. 2018
Cirillo G, Di Pino G, Capone F, Ranieri F, Florio L, Todisco V, Tedeschi G, Funke K, Di Lazzaro V. Neurobiological after-effects of non-invasive brain stimulation. Brain Stimul. 2017
Dileone M, Ranieri F, Florio L, Capone F, Musumeci G, Leoni C, Mordillo-Mateos L, Tartaglia M, Zampino G, Di Lazzaro V. Differential Effects of HRAS Mutation on LTP-Like Activity Induced by Different Protocols of Repetitive Transcranial Magnetic Stimulation. Brain Stimul. 2016
Di Lazzaro V, et al. Val66Met BDNF gene polymorphism influences human motor cortex plasticity in acute stroke. Brain Stimul. 2015
Tommaso Sanna, Hans-Christoph Diener, Rod S. Passman, Vincenzo Di Lazzaro, Richard A. Bernstein Carlos A. Morillo, Marilyn Mollman Rymer, Vincent Thijs, Tyson Rogers, Frank Beckers, Kate Lindborg, and Johannes Brachmann. Cryptogenic Stroke and Underlying Atrial Fibrillation. N Engl J Med 2014
Corbetto M, Capone F, Denaro V, Quattrocchi C, Colosimo C, Maira G, Di Lazzaro V. Clinical Reasoning: A case of slowly progressive painful paraparesis. neurology. 2014
Di Lazzaro V. Biological effects of non-invasive brain stimulation. Handb Clin Neurol. 2013
Di Lazzaro V, et al. The Level of Cortical Afferent Inhibition in Acute Stroke Correlates With Long-Term Functional Recovery in Humans. stroke. 2012
Profice P, Pilato F, Broccolini A, Santoliquido A, Brand GD, Di Lazzaro V. Right hemiparesis in right carotid stenosis. circulation. 2011
Di Lazzaro V, et al. Tired legs - a gut diagnosis Lancet. 2010
Di Lazzaro V, et al. Associative Motor Cortex Plasticity: Direct Evidence in Humans. Cerebral cortex 2009
Di Lazzaro V, et al. Functional Evaluation of Cerebral Cortex in Dementia with Lewy Bodies Neuroimage 2007
Di Lazzaro V, et al. In vivo Cholinergic Circuit Evaluation in Frontotemporal and Alzheimer Dementias. Neurology 2006
Di Lazzaro V, et al. The Role of Motor Evoked Potentials in Diagnosis of Cauda Equina and Lumbosacral Cord Lesions. Neurology 2004
Di Lazzaro V, et al Effects of Vagus Nerve Stimulation on Cortical Excitability in Epileptic Patients. Neurology 2004
Di Lazzaro V, et al. Non-invasive in vivo assessment of cholinergic cortical circuits in Alzheimer's disease using transcranial magnetic stimulation. Neurology 2002
Peter Brown, Antonio Oliviero, Paolo Mazzone, Angelo Insola, Pietro Tonali, and Vincenzo Di Lazzaro Dopamine Dependency of Oscillations between Subthalamic Nucleus and Pallidum in Parkinson's Disease. Journal of Neuroscience 2001
