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Role of oral microbiota as a potential predictor of response to immunotherapy treatments in non-small cell lung cancer

Project objectives

  • Identification of a specific composition of the oral microbiota capable of predicting the benefit of immunotherapy treatments in patients with advanced non-small cell lung cancer
  • Analysis of specific metabolites produced by the identified bacterial species to evaluate their ability to modulate the immune system and response to immunotherapy
  • Evaluation of a possible modulation of the composition of the oral microbiota through specific dietary interventions and/or through the use of antibiotics to make the patient responsive to treatment

Start and end date

November 2021 – ongoing (July 2024 approximate end date)

Project Manager

Francesco Pantano (PI)

Coordinating institution of the project

Università Campus Bio-Medico di Roma

Other Institutions involved

  • Analysis Laboratory, Campus Bio-Medico University Hospital Foundation 
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