The areas of study: lung cancer, type 1 diabetes, ergonomic evaluations and low back pain
August 20, 2020 - One year after the start, the first results of the strategic projects UCBM.
Is called OxIDIA the project for the study and development of a new type 1 diabetes biomarker. “We tested antibodies against the oxidized insulin ox-Ptm-Ins-Ab in over 600 children followed from birth until the development of type 1 diabetes - Explains Nicola Napoli –. We then studied the prevalence of complications in 153 type 1 diabetics, with long disease duration, in relation to ox-Ptm-Ins-Ab. From the isolation of mononuclear cells from peripheral blood we are analyzing the epigenetic modifications. Finally, the electronics unit for sensory systems has already optimized an electrochemical sensor for the detection of oxidized insulin".
In the non-small cell lung cancer research (CLARO), 148 of 150 patients are enrolled. “To test the radiomic predictive model with respect to overall survival - highlights Sara Ramella - a retrospective analysis was performed on 100 patients affected by this third stage malignancy with an accuracy of 83.5%. The analysis identified the subjects who best responded to radiation treatment with an accuracy of 82%. Furthermore, the volume of interest from which to extract the constituent features of the predictive model resulted in the clinical target volume, consisting not only of the neoplasm, but also of the immediately neighboring tissues".
The project HOPE, which sees the participation of nine Research Units UCBM and one from the Milan Polytechnic, aims to improve the quality of life of patients suffering from low back pain. “The main results relate to the development of sensors to be integrated into a wearable system capable of monitoring physiological, environmental and posture parameters - Explains Emiliano Schena - In addition, a module dedicated to monitoring posture was developed and tested on healthy volunteers, based on fiber optic sensors capable of carrying out measurements distributed along the spinal column"..
The project aims to analyze the movements of nurses and health workers SAFE MOVER. “The experimental setup for ergonomic assessment, biomechanical and psychophysiological analysis of healthcare workers and patients during patient handling activities has been developed - he claims Loredana Zollo –. Concepts were developed for the design of the new robotic device and tools for evaluating the efficacy, functionality, safety and acceptability of the solutions proposed by healthcare personnel and patients".
