Prof.ssa Francesca Zalfa
Biography
Associate Professor of Applied Biology since 2015 at the Departmental Faculty of Medicine and Surgery, he is present at theUniversità Campus Bio-Medico di Roma since 2007, where he is a professor of Biology and Coordinator of the Integrated Courses in Biology and Genetics (CdS Medicine), Chemistry and Biological Sciences (CdS TRMIR) and Biology and Biochemistry (CdS Physiotherapy). From 2014 to today he has also carried out healthcare activities as a Molecular Biologist at the Complex Pathological Anatomy Structure of the Polyclinic UCBM. It carries out research activities in the study of the molecular and cellular mechanisms of tumor progression with a scientific production with total impact factor > 230, total citations > 1800 and h-index = 20.
Curriculum
EDUCATION AND TRAINING
- From March 2015: Associate Professor of Applied Biology. UCBM, Rome.
- 2014: National Scientific Qualification for the functions of Associate Professor in the competition sector 05/F1-Call 2012 (DD n.222/2012)
- From 2010 to 2015: RTDA Researcher in Applied Biology, UCBM.
- From 2004 to 2010: Post Doc Position at the University of Rome Tor Vergata and at the Santa Lucia IRCCS Foundation in Rome.
- 2004: PhD in Cellular and Molecular Biology, University of Rome "Tor Vergata".
- 2001: Degree in Biological Sciences, University of Rome "Tor Vergata".
ACADEMIC POSITIONS
- From 2019 to today - Member of the University Evaluation Unit, UCBM
- From 2017 to today - Member of the Commission for Specialization Schools in Radiodiagnostics and Gynecology and Obstetrics, Faculty of Medicine, UCBM.
- From 2017 to 2019 - Member of the Commission for the State Examination for the Qualification to Practice the Profession of Doctor, UCBM.
- From 2017 to 2019 – Member of the Doctoral School in Science and Engineering for Man and the Environment, Faculty of Engineering, UCBM.
- From 2016 to today – Member of the Italian Association of Biology and Genetics (AIBG).
- From 2016 to 2019 - Member of the AQD group of the CdS in Medicine and Surgery, Departmental Faculty of Medicine, UCBM.
- From 2015 to today – Member of the Council of the Departmental Faculty of Medicine and Surgery.
- From 2015 to today - Lecturer of Reference for the Course in Medicine and Surgery, Faculty of Medicine, UCBM.
- Since 2015: Member of the Commission and Co-supervisor for the dissertation of the degree theses for the degree course in Medicine and Surgery, UCBM.
- Since 2010: Member of the commission for the dissertation of degree theses for the CdS in TRR, UCBM.
ASSISTANCE DUTIES
From 2019 to today - Assignment for assistance activity as Molecular Biologist at the UOS of Predictive Molecular Diagnostics of the Polyclinic UCBM.
From 2014 to 2019 - Assignment for assistance activity as Molecular Biologist at the UOC of Pathological Anatomy.
TEACHING ACTIVITY
- From 2010 to present: Professor of Applied Biology and Coordinator of integrated courses in Biology and Genetics (CdS in Medicine and Surgery), Chemistry and Biological Sciences (CdS in TRMIR) and Biology and Biochemistry (CdS in Physiotherapy) UCBM, Rome.
- From 2010 to 2013: Professor of Applied Biology for the Course in Nursing Sciences, UCBM.
- 2009: Adjunct professor of Biology for the Degree Courses in Dietetics, Biomedical Laboratory Techniques and Audioprosthesis Techniques. University of Rome "Tor Vergata".
- 2006/2007: Teaching of Transgenic Organisms for the CdS in Biological Sciences, University of Rome "Tor Vergata".
SCHOLARSHIPS AND PRIZES
- 2005: Award for the best PhD thesis (XVII PhD cycle in Cellular and Molecular Biology), University of Rome "Tor Vergata", Faculty of Sciences.
- 2004: Scholarship from the Italian Fragile X Syndrome Association.
- 2001: Human Frontier Science Program Scholarship (HFSPO).
- 2001: Adriano Buzzati Traverso Foundation Award.
SCIENTIFIC PRODUCTION
Author of 31 scientific articles published in peer reviewed international journals. Total impact factor = 234,73; Total citations > 1800; H-index = 20 (updated in December 2022).
PUBLICATIONS
PUBLICATIONS OF THE LAST 5 ACADEMIC YEARS:
- Zalfa F, Perrone MG, Ferorelli S, Laera L, Pierri CL et al. (2022) Genome-Wide Identification and Validation of Gene Expression Biomarkers in the Diagnosis of Ovarian Serous Cystadenocarcinoma. Cancers (Basel). 14:3764.
- Pantano F, Zalfa F, Iuliani M, Simonetti S, Manca P et al. (2022) Large-Scale Profiling of Extracellular Vesicles Identified miR-625-5p as a Novel Biomarker of Immunotherapy Response in Advanced Non-Small-Cell Lung Cancer Patients. Cancers (Basel). 14:2435.
- Carotti S, Lettieri-Barbato D, Piemonte F, Ruggiero S, Rosina M, Zalfa F et al. (2021) Molecular and histological traits of reduced lysosomal acid lipase activity in the fatty liver. Cell Death Dis. 12:1092.
- Carotti S, Zingariello M, Francesconi M, D'Andrea L, Latasa MU, Colyn L, Fernandez-Barrena MG, Flammia RS, Falchi M, Righi D, Pedini G, Pantano F, Bagni C, Perrone G, Rana RA, Avila MA, Morini S, Zalfa F. (2021) Fragile X mental retardation protein in intrahepatic cholangiocarcinoma: regulating the cancer cell behavior plasticity at the leading edge. Oncogene. 23:4033-4049 .
- Schettini F, Chic N, Brasó-Maristany F, Paré L, Pascual T, Conte B, Martínez-Sáez O, Adamo B, Vidal M, Barnadas E, Fernández-Martinez A, González-Farre B, Sanfeliu E, Cejalvo JM , Perrone G, Sabarese G, Zalfa F et al. (2021) Clinical, pathological, and PAM50 gene expression features of HER2-low breast cancer. NPJ Breast Cancer. 7(1):1.
- Carotti S, Aquilano K, Zalfa F, Ruggiero S, Valentini F et al. (2020) Lipophagy Impairment Is Associated With Disease Progression in NAFLD. Front Physiol. 11:850.
- Zalfa F, Panasiti V, Carotti S, Zingariello M, Perrone G, Sancillo L, Pacini L, Luciani F, Roberti V, D'Amico S, Coppola R, Abate SO, Rana RA, De Luca A, Fiers M, Melocchi V, Bianchi F, Farace MG, Achsel T, Marine JC, Morini S, Bagni C. (2017) The fragile X mental retardation protein regulates tumor invasiveness-related pathways in melanoma cells. Cell Death Dis. 8:e3169.
- Filippini A, Bonini D, Lacoux C, Pacini L, Zingariello M, Sancillo L, Bosisio D, Salvi V, Mingardi J, La Via L, Zalfa F, Bagni C, Barbon A (2017) Absence of the Fragile X Mental Retardation Protein results in defects of RNA editing of neuronal mRNAs in mice. RNA Biol. 02:15 pm80-1591.
- Fernandez-Martinez A, Pascual T, Perrone G, Morales S, de la Haba J, González-Rivera M, Galván P, Zalfa F, Amato M, Gonzalez L, Prats M, Rojo F, Manso L, Paré L, Alonso I, Albanell J, Vivancos A, González A, Matito J, González S, Fernandez P, Adamo B, Muñoz M, Viladot M, Font C, Aya F, Vidal M, Caballero R, Carrasco E, Altomare V, Tonini G, Prat A, Martin M. (2017) Limitations in predicting PAM50 intrinsic subtype and risk of relapse score with Ki67 in estrogen receptor-positive HER2-negative breast cancer. Oncotarget. 8:21930-21937 .
- Carotti S, Perrone G, Amato M, Vespasiani Gentilucci U, Righi D, Francesconi M, Pellegrini C, Zalfa F, Zingariello M, Picardi A, Onetti Muda A, Morini S. (2017) Reelin expression in human liver of patients with chronic hepatitis C infection. Eur J Histochem. 61:2745.
- Ferrari S, Caschera L, Deda G, Amato M, Annibali O, Rabitti C, Crescenzi A, Petitti T, Avvisati G, Onetti Muda A, Zalfa F* and Bianchi A*. (2016) A Feasible Flowchart to Screen EBV-Positive Diffuse Large B Cell Lymphoma of the elderly: A Molecular Approach. APALM. 3:2349-6983 . * Share last authorship
