Performance evaluation of Fully Automated Real Time PCR approach (IDylla®) for RAS and BRAF mutation detection in clinical practice of metastatic ColorEctal Cancer patients: an Italian multicenter STUDY
Project objectivesMain goal Prospective evaluation of the effectiveness of the combined use of the CE-IVD Idylla™ KRAS and NRAS/BRAF Mutation Tests, in the identification of clinically relevant mutations in patients with colon cancer undergoing treatment with anti-EGFR drugs. Secondary objective Retrospective comparison of IDYLLA-RAS-WT results with those obtained by NGS, to verify the presence and clinical significance of low allelic frequency mutations. |
Start and end date |
| 17 December 2019 - 03 May 2021 |
Project Manager |
| Prof. Giuseppe Perrone - Principal Investigator |
Coordinating institution of the project |
| Department of Public Health, University of Naples “Federico II” |
Other Institutions involved |
|
