Molecular biology analysis in patients with diffuse large B-cell lymphoma

Project objectives

The aim of the study is to describe the molecular and clinical characteristics of a retrospective cohort of patients and to correlate the potential role of genetic mutations with the clinical course and M1/M2 status of tumor associated macrophages (TAMs). The genetic mutations evaluated will be p53 and MYD 88 with a molecular biology technique on the histological preparation of the lymph node biopsy.

Start and end date

01/04/2014 - ongoing

Project Manager

Prof. Giuseppe Avvisati

Coordinating institution of the project

Università Campus Bio-Medico di Roma

Other Institutions involved

Center de Investigation of Cancer - Salamanca

Funding source(s).

• Hematology Research Unit Università Campus Bio-Medico di Roma

• Research laboratory of the University of Salamanca