Letizia Chiodo

Associate Professor in Theoretical Physics of Matter.

Degree in Physics, 2002, University of Rome La Sapienza.

PhD in Physics, 2006, University of Rome Tor Vergata.

Letizia Chiodo she carried out research as a postdoc researcher at the CNR-Nanotechnology Laboratory of Lecce (2006-2008), at the Department of Materials Physics of the University of the Basque Country (2008-2010), and at the Italian Institute of Technology (2010- 2015).

From 2016 to 2023 she was a researcher in Theoretical Physics of Matter at the Department of Engineering of the Campus Bio-Medico University, Research Unit of Nonlinear Physics and Mathematical Models.

Expert in theoretical and computational methods for studying the physical properties of inorganic materials and biological systems.

Main research lines: optical and electronic properties of low-dimensional materials; structure-function of membrane proteins; lncRNA-protein interaction; biophysical models of neurons and neuronal networks.

Member of the Steering Committee of the European Theoretical Spectroscopy Facility - ETSF (since 2018)

Visiting professor at the Physics Department of the University of Cagliari (2009)

Visiting Professor at Nano-Bio Spectroscopy Group and European Theoretical Spectroscopy Facility (ETSF), Department of Physics of Materials, University of the Basque Country (2008)

Member of the Academic Board of the PhD in Science and Engineering for Man and the Environment, UCBM (since 2017), and of the Academic Board of the PhD in Bioengineering, Biosciences and Intelligent Systems (since 2022).

Responsible for numerous national (ISCRA-CINECA) and European (PRACE, DECI, ICHEC, BSC) computational projects (HPC).

Participant in the Horizon-Europe project "Multiscale quantum bio-imaging and spectroscopy – MUQUABIS" (2022-2026).

Participant of the Working Group for the drafting of the Gender Equality Plan - GEP of UCBM (2021-2022).

Head of Research Unit at UCBM as part of the PRIN PNRR 2022 project "RNA secondary structures and their relationship with function: application to non-coding RNAs - RNA2Fun"

Recent articles (for the complete list of publications, see https://scholar.google.it/citations?hl=it&user=U-Oq1BgAAAAJ&view_op=list_works or https://orcid.org/my-orcid?orcid=0000-0002 -8278-7075)

- Assessment of tools for RNA secondary structure prediction and extraction: a final-user perspective, MAG Matarrese, et al., Journal of Biomolecular Structure & Dynamics (2022). doi: 10.1080/07391102.2022.2116110

- In silico conformational features of botulinum toxins A1 and E1 according to intraluminal acidification”, G. Cottone, et al., Toxins 14(9), 644 (2022). OA. doi:10.3390/toxins14090644

- Multiscale Hybrid Modeling of Proteins in Solvent: SARS-CoV2 Spike Protein as test case for Lattice Boltzmann - All Atom Molecular Dynamics Coupling, M. Lauricella, et al., Communications in Computational Physics (2022)

- Computational methods and theory for ion channel research, C. Guardiani, et al., Advances in Physics: X 7, 2080587 (2022). OA. doi: 10.1080/23746149.2022.2080587

- Inferring excitatory and inhibitory connections in neuronal networks, S. Ghirga, et al. Entropy 23(9), 1185 (2021).

- A shearless microfluidic device detects a role in mechanosensitivity for AWCON neuron in C. elegans, D. Caprini, et al., Advanced Biology 2100927 (2021).

- Thermodynamics and kinetics of ion translocation in the human wild-type and E-1ʹA α7 nicotinic receptor”, G. Cottone, et al., Nuovo Cimento C, 44, 4-5, 127 (2021).

- Biophysics and modeling of mechanotransduction in neurons: a review, M. Nicoletti, et al. Mathematics 9, 323 (2021).

- Thermodynamics and kinetics of ion permeation in wild-type and mutated open active conformation of the human α7 nicotinic receptor, G. Cottone, et al., J. Chem. Inf. Model. 60, 10, 5045–5056 (2020)

- Improved transition metal surface energies from a generalized gradient approximation developed for quasi two-dimensional quantum systems, A. Patra, et al., J. Chem. Phys. 152, 151101 (2020).

- Hepatitis B protein HBx binds the DLEU2 lncRNA to sustain cccDNA and host cancer-related gene transcription, D. Salerno, et al., Gut 69, 2016-2024 (2020).

- Ab initio accelerated molecular dynamics study of the hydride ligands in the ruthenium complex: Ru(H2)2H2(P(C5H9)3)2, M. Lauricella, et al., Phys Chem Chem Phys 21, 25247-25257 (2019) .

- Biophysical modeling of β-cell networks: realistic architectures and heterogeneity effects, A. Loppini, L. Chiodo, Biophys. Chem. 254, 106247 (2019).

- Biophysical modeling of C. elegans neurons: single ion currents and whole-cell dynamics of AWCon and RMD, M. Nicoletti, et al., PLoS ONE 14(7): e0218738 (2019).

- Two-dimensional innovative materials for photovoltaics, L. Chiodo, Current Opinion in Green and Sustainable Chemistry 17, 49-56 (2019)

- Closed-locked and apo-resting state structures of the human α7 nicotinic receptor: a computational study, L. Chiodo, et al., J Chem Inf Model 58, 2278 (2018)

- A possible desensitized state conformation of the human α7 nicotinic receptor: A molecular dynamics study, L. Chiodo, et al., Biophys. Chem. 229, 99-109 (2017).

- Strongly bound excitons in anatase TiO2 single crystals and nanoparticles, E Baldini, et al., Nature communications 8 (1), 13 (2017).

- HBx/DLEU2/EZH2 co-regulation of host genes expression in HCC, F Guerrieri, et al., J. Hepatology 68, S687-S688

- Anomalous anisotropic exciton temperature dependence in rutile TiO2, E Baldini, et al., Phys. Rev. B 96, 041204 (2017)

- The binding of the DLEU2 lncRNA to HBx and the cccDNA affects viral chromatin transcription in HBV infected cells, F Guerrieri, et al.,HEPATOLOGY 64, 315A-316A (2016)

- Emerging giant resonant exciton induced by Ta substitution in anatase TiO 2: A tunable correlation effect, Z Yong, et al., Phys. Rev. B 93 (20), 205118 (2016)