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MP-LALC- Maintainance Pembrolizumab in Locally Advanced Lung Cancer

Project objectives

A randomized phase II study of pembrolizumab (MK3475) as maintenance therapy in patients with inoperable stage III non-small cell lung cancer (NSCLC) who have undergone definitive chemoradiation. The purpose of this study is to evaluate whether maintenance treatment with pembrolizumab (24 months) prolongs disease-free survival compared to observation alone in patients with stage III non-small cell lung cancer (NSCLC) who are not eligible for surgical resection and who have achieved a response or stable disease following chemoradiation.

Start and end date

January 2018 - ongoing

Project managers

prof Sara Ramella

Coordinating institution of the project

University of Turin

Funding sources

No profit

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