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Rs738409 single nucleotide polymorphism (SNP) in the patatin-like phospholipase domain containing-3 (PNPLA) gene and its correlation with the risk of progression to cirrhosis in NAFLD patients

Rs738409 single nucleotide polymorphism (SNP) in the patatin-like phospholipase domain containing-3 (PNPLA) gene and its correlation with the risk of progression to cirrhosis in NAFLD patients

Project objectives

To evaluate how different genotypes of the PNPLA3 rs738409 polymorphism can predict the development of cirrhosis secondary to nonalcoholic steatohepatitis.

Start and end date

Enlistment began in 2014 - August 2015

Project Manager

  • prof Elisabetta Riva - molecular analysis
  • Dr. U. Vespasiani - clinical part
  • Prof. A. Picardi - clinical part

Project coordinating institution

Università Campus Bio-Medico di Roma

Source of funding

 

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