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DKKs and signalsing Wnt/beta-catenin as possible mediators of the inflammatory and fibrotic process in Systemic Sclerosis
Project objectives
To evaluate circulating protein levels of the DKK and Wnt/beta-catenin systems in the serum of SSc patients versus healthy controls and their correlation with disease manifestations.
To evaluate the protein levels of the DKK and Wnt/beta-catenin systems in the dermis of SSc patients and their correlation with disease characteristics.