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DKKs and signalsing Wnt/beta-catenin as possible mediators of the inflammatory and fibrotic process in Systemic Sclerosis

Project objectives

  • To evaluate circulating protein levels of the DKK and Wnt/beta-catenin systems in the serum of SSc patients versus healthy controls and their correlation with disease manifestations.
  • To evaluate the protein levels of the DKK and Wnt/beta-catenin systems in the dermis of SSc patients and their correlation with disease characteristics.

Start and end date

July 2023 - September 2024

Project Manager

Prof. Roberto Giacomelli - Principal Investigator

Coordinating institution of the project

UCBM
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