Evaluating the effectiveness of a combination of hyaluronic acid and chondroitin sulfate used in parallel with a proton pump inhibitor in patients with gastroesophageal non-erosive reflux disease "NERD" - a clinical, multicenter, randomized, double-blind, placebo-controlled and parallel-group investigation
Project objectives
Multicenter clinical, randomized, double-blind, parallel-group, placebo-controlled protocol aims to evaluate the effect of Esoxx® added to proton pump inhibitors (standard therapy) on typical symptoms of NERD and quality of life. The study also aims to evaluate the tolerability, adherence to therapy and palatability of Esoxx®.
Start/End Date
January, 2013 - June, 2013
Principal Investigator
Prof. Michele Cicala
Host Institution
Ospedale San Martino, Unit of Gastroenterology and Digestive Endoscopy - Genoa, Italy
Source of funding
Clinical protocol sponsored by Alfa Wassermann SpA