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Identification of “signalling circulating molecules capable of predicting tumor dissemination in the bone marrow in patients with early breast cancer

Project objectives

  • Assess the presence of tumor cells disseminated in the bone marrow (DTC)
  • Analyze the role of the “signaling” miR-30/ITGA5 in promoting DTC colonization 
  • Evaluate the role of the “signaling” miR-30/ITGA5 in the modulation of immune system cells

Start and end date

September 2022 – ongoing (December 2025 approximate end date)

Project Manager

Francesco Pantano (PI)

Coordinating institution of the project

Università Campus Bio-Medico di Roma

Other Institutions involved

  • University of Amsterdam
  • Medical University of Gdańsk
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