RESET

Project objectives

The Rectal Surgery Evaluation Trial (RESET) is a prospective, observational, case-matched, multicenter study of four cohorts designed to study TME with LAR using open laparotomy, laparoscopy, robot-assisted surgery, or transanal surgery in high-risk patients surgery with medium-low, non-metastatic rectal cancer. All surgeries are performed by surgeons who are experts in a technique. Oncological, morbid and functional outcomes will be assessed in a composite primary outcome, with success defined as circumferential resection margin ≥1 mm, TME grade III and minimal postoperative morbidity (absence of Clavien-Dindo grade III-IV complications within 30 days after surgery). Secondary endpoints will include long-term (2-year) co-primary endpoints, quality of surgery, quality of life, length of hospital stay, operative time and rate of unplanned conversions. Comparative data for these techniques are needed to provide clinical data on the surgical management of rectal tumors using surgery.

Start and end date

Project Manager

Coordinating institution of the project

Other Institutions involved

• CBM

Funding source(s).