On October 26 with prof. Mark Capogna

October 20, 2015 - It will be held on 26 October 2015 at 05:30 pm at the Conference Hall of the PRABB the didactic seminar "Synaptic plasticity: from Hebb's model to contemporary theories". On this occasion the prof. Mark Capognafrom the Oxford University Department of Pharmacology.

The seminar will illustrate molecular, cellular and physiological aspects of synapses of the central nervous system. Particular space will be devoted to short- and long-term synaptic plasticity. Examples of induction and maintenance of synaptic plasticity will be shown. Plasticity phenomena occur in excitatory glutamatergic neuronal connections, as predicted by Hebb's model, but also in inhibitory GABAergic neuronal connections, as demonstrated by more recent models and experimental data. Finally, it will be shown that synaptic plasticity may represent a fundamental cellular mechanism for functional recovery in neurodegenerative diseases or movement disorders. This aspect could lead to the use of selective electrical stimulation to induce synaptic plasticity in key neuronal connections, as a therapeutic treatment.

The professor. Capogna will also speak at 12:30 pm on the same day, again in the PRABB Conference Room, at the scientific seminar entitled "GABAergic neuron diversity in the hippocampus-amygdala circuit in health and disease".